Güncel Gönderiler: PubMed İndeksli Yayınlar Koleksiyonu
Toplam kayıt 1136, listelenen: 81-100
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Phytochemical and Biological Investigations of Crude Extracts of Astragalus pisidicus
(Mdpi, 2025)Background/Objectives: Astragalus L. is a genus of the Fabaceae family, encompassing over 3000 species globally, with 380 species found in Turkey. This is the inaugural examination of the phytochemical, antioxidant, ... -
Oxylipins Derived from PUFAs in Cardiometabolic Diseases: Mechanism of Actions and Possible Nutritional Interactions
(Mdpi, 2024)Oxylipins are oxidized fatty acids, both saturated and unsaturated, formed through pathways that involve singlet oxygen or dioxygen-mediated oxygenation reactions and are primarily produced by enzyme families such as ... -
Global Trends and Developments in Diet and Longevity Research: A Bibliometric Analysis
(Mdpi, 2025)Background/Objectives: The global population is rapidly aging, raising interest in dietary practices for promoting the healthspan. This study aimed to comprehensively investigate the state of diet and longevity research ... -
Unveiling the Phytochemical Diversity and Bioactivity of Astragalus melanophrurius: A First Report Integrating Experimental and In Silico Approaches
(Mdpi, 2025)Background: The genus Astragalus is renowned for its diverse bioactive potential, yet the chemical composition and biological properties of Astragalus melanophrurius remain inadequately explored. This study aimed to ... -
The Anthelmintic Activity of Nepeta racemosa Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies
(Mdpi, 2025)Gastrointestinal nematodes (GINs) inflict significant economic losses on sheep and goat farming globally due to reduced productivity and the development of anthelmintic resistance. Sustainable control strategies are urgently ... -
Inhibition of Monoamine Oxidases by Pyridazinobenzylpiperidine Derivatives
(Mdpi, 2024)Monoamine oxidase inhibitors (MAOIs) have been crucial in the search for anti-neurodegenerative medications and continued to be a vital source of molecular and mechanistic diversity. Therefore, the search for selective ... -
Human Breast Milk Exosomes: Affecting Factors, Their Possible Health Outcomes, and Future Directions in Dietetics
(Mdpi, 2024)Background: Human breast milk is a complex biological fluid containing multifaceted biological compounds that boost immune and metabolic system development that support the short- and long-term health of newborns. Recent ... -
Illuminating Bilateral Breast Cancer: A Multicenter Experience and Clinical Observations
(Mdpi, 2025)Background and Objectives: Although breast cancer is the most common type of cancer among women, bilateral breast cancer (BBC) remains exceedingly rare. BBC can present as either synchronous (SBBC) or metachronous (MBBC) ... -
Impact of Kefir on the Gut-Brain Axis: Serotonin Metabolism and Signaling in Pediatric Rats
(Mdpi, 2025)Serotonin (5-hydroxytryptamine) is a key neurotransmitter involved in gastrointestinal and central nervous system functions. Given that approximately 90% of serotonin is synthesized in the gut, dietary interventions targeting ... -
Survival Outcomes in Metastatic Germ Cell Tumors: A Multicenter Study from Turkey
(Mdpi, 2025)Background/Objectives: Metastatic testicular germ cell tumor (mGCT) is a highly curable disease with first-line cisplatin-based combination chemotherapy. This study aims to evaluate the clinicopathological characteristics ... -
Evaluation of the Effect of Different Inhalation Agents on Ovaries with Hyperthermic Intraperitoneal Chemotherapy: An Experimental Study
(Mdpi, 2024)Background and Objectives: Cisplatin is a chemotherapeutic drug that is frequently used with hyperthermic intraperitoneal chemotherapy (HIPEC). Cisplatin-induced gonadotoxicity leads to a depletion of the ovarian reserve, ... -
Integration of Postbiotics into Adult Diapers: In Vitro Evaluation of Biocompatibility and Effect on Skin Microbiota
(Mdpi, 2025)Postbiotics are bioactive microbial metabolites recognized for their potential to support skin health and balance the microbiota. In this study, nonwoven fabrics and adult diaper prototypes, with and without postbiotic ... -
Impact of Juglone, a PIN1 İnhibitor, on Oral Carcinogenesis Induced by 4-Nitroquinoline-1-Oxide (4NQO) in Rat Model
(Mdpi, 2024)Background and Objectives: PIN1 is overexpressed in several human cancers, including prostate cancer, breast cancer, and oral squamous carcinomas. Juglone (J), derived from walnut, was reported to selectively inhibit PIN1 ... -
Galectin-3 Release in the Bone Marrow Microenvironment Promotes Drug Resistance and Relapse in Acute Myeloid Leukemia
(Mdpi, 2025)Reciprocal signaling between acute myeloid leukemia (AML) cells and the surrounding bone-marrow microenvironment (BMME) promotes AML progression through several mechanisms. One of the most important mechanisms is the ... -
Retrospective Evaluation of Survival and Prognostic Factors in Immune Thrombocytopenia: A Single-Center and Cross-Sectional Study
(Mdpi, 2024)Background and Objectives: Immune thrombocytopenia (ITP) is an autoimmune disease characterized by the autoantibody-mediated destruction of platelets. The treatment of ITP aims to maintain a sufficient platelet count to ... -
Mangiferin Induces Post-Implant Osteointegration in Male Diabetic Rats
(Mdpi, 2024)Background and Objectives: Hyperglycemia is known to undermine the osteointegration process of implants. In this study, the effects of mangiferin (MF) on the post-implant osteointegration process in a type-II diabetes model ... -
Fracture Resistance of Endodontically Treated Teeth Restored with Preheated Short Fiber-Reinforced Composite and Preheated Composite Resin
(Mdpi, 2025)This study aimed to assess the fracture resistance and fracture patterns of endodontically treated permanent mandibular molars restored with either preheated or nonpreheated conventional composite resin or short fiber-reinforced ... -
Induction or Adjuvant Chemotherapy in Patients with Locally Advanced Nasopharyngeal Cancer Receiving Chemoradiotherapy? A Turkish Oncology Group Study
(Mdpi, 2025)Background/Objectives: In this retrospective study, we aimed to compare the efficacy, survival, and toxicity results of induction (IC) or adjuvant (AC) treatment with chemoradiotherapy (CRT) in locally advanced nasopharyngeal ... -
Anti-Cataract Effect of the Traditional Aqueous Extract of Yerba Mate (Ilex paraguariensis A. St.-Hil.): An In Ovo Perspective
(Mdpi, 2024)Introduction: The therapeutic effect of different doses of the traditional aqueous extract of dried leaves of yerba mate (Ilex paraguariensis A. St.-Hil.) was investigated in an experimental cataract model in chicken ... -
The Association Between Premature Ejaculation and Non-Dipper Blood Pressure: A Cross-Sectional Study
(Mdpi, 2025)Background/Objectives: Premature ejaculation (PE) is one of the most common sexual problems in men. Autonomic nervous system (ANS), which is an important determinant of circadian changes in blood pressure (BP), also has a ...
