dc.contributor.author | Çalışkan, Mustafa | |
dc.contributor.author | Beysel, Selvihan | |
dc.contributor.author | Kızılgül, Muhammed | |
dc.contributor.author | Özbek, Mustafa | |
dc.contributor.author | Çakal, Erman | |
dc.date.accessioned | 2021-05-05T22:14:17Z | |
dc.date.available | 2021-05-05T22:14:17Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1300-0144 | |
dc.identifier.issn | 1303-6165 | |
dc.identifier.uri | https://doi.org/10.3906/sag-1904-49 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12933/407 | |
dc.description | WOS:000504051300011 | en_US |
dc.description | PubMed: 31655512 | en_US |
dc.description.abstract | Background/aim: This study aimed to investigate the change in bone mineral density (BMD) before and 1 year after parathyroidectomy in patients with primary hyperparathyroidism (PHPT). Materials and methods: The clinical and biochemical parameters and DEXA screening of patients with symptomatic PHPT (n = 28) and asymptomatic PHPT (n = 63) were investigated before and 1 year after parathyroidectomy. Results: Patients with symptomatic PHPT had a higher prevalence of nephrolithiasis (18.2% vs. 4.6%, P = 0.032) when compared to the prevalence in patients with asymptomatic PH PT. The prevalence of osteoporosis in the lumbar spine (63.0% vs. 37.5%, P = 0.026) and femoral neck (40.7% vs. 20.6%, P = 0.048) was higher in symptomatic PHPT when compared to the prevalence in asymptomatic PHPT. After parathyroidectomy, the decreases in the prevalence of osteoporosis in the lumbar spine (25.8% vs. 9.4%, P = 0.014), femoral neck (22.1% vs. 8.2%, P = 0.009), and total hip (22.4% vs. 5.3%, P = 0.007) were higher in symptomatic PHPT compared to the asymptomatic PHPT group. A higher BMD gain (g/cm(2)) was seen in the lumbar spine (10.83% vs. 4.65%, P=0.016) and femoral neck (12.61% vs. 4.37%, P=0.005) in symptomatic PHPT compared to the asymptomatic PHPT group. Conclusion: Parathyroidectomy provided more BMD gain in the lumbar spine and femoral neck in patients with symptomatic PHPT when compared to patients with asymptomatic PHPT 1 year after parathyroidectomy. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Tubitak Scientific & Technical Research Council Turkey | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Bone mineral density | en_US |
dc.subject | parathyroidectomy | en_US |
dc.subject | hyperparathyroidism | en_US |
dc.title | The effect of parathyroidectomy on bone mineral density in primary hyperparathyroidism | en_US |
dc.type | article | en_US |
dc.department | AFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.contributor.institutionauthor | Beysel, Selvihan | |
dc.identifier.doi | 10.3906/sag-1904-49 | |
dc.identifier.volume | 49 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 1674 | en_US |
dc.identifier.endpage | 1680 | en_US |
dc.relation.journal | Turkish Journal Of Medical Sciences | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |