Examination of 25-Hydroxyvitamin D Levels in Patients With Benign Positional Paroxysmal Vertigo

Abstract

Aim: Benign paroxysmal positional vertigo (BPPV) is a prevalent cause of vertigo and dizziness. This study aimed to evaluate serum 25-hydroxyvitamin D [25(OH)-D] levels in patients diagnosed with posterior canal BPPV (PCBPPV) who presented to our clinic with dizzines complaints and healty induviduals without dizzines, and to investigate the association between low serum 25(OH)-D levels and BPPV. Material and Method: Between January 2022 to March 2023, 50 patients (25 females, 25 males) with PCBPPV and 50 healthy controls (24 females, 26 males) without dizziness were enrolled. Serum 25(OH)-D levels of both groups were compared. Results: Serum 25(OH)-D levels were significantly lower in the BPPV group compared to the control group (p=0.031). Serum 25(OH)-D levels were 20ng/mL or belowin 37 patients (74%) in the patient group (mean: 14.25±3.90), while this was observed in 28 induviduals (56%) in the control group (mean: 15.94±2.19). Conclusion: Patients with BPPV exhibited significantly lower 25(OH)-D levels than healthy controls. These findings suggest that assessing vitamin D deficiency in BPPV patients may provide valuable insights into disease mechanisms and guide clinical management. Low 25(OH)-D levels appear to contribute to BPPV development.