Comparison of Platelet Mass Index in On-Pump and Off-Pump Coronary Artery Bypass Surgery

Abstract

Introduction: Platelet mass index (PMI) is calculated by multiplying platelet count and mean platelet volume (MPV). It demonstrates platelet activation and is thought to be associated with inflammation. Its importance for cardiac surgery has not yet fully been clarified. This study investigates whether there is a difference between PMI levels after on-pump and off-pump coronary artery bypass surgery and the relationship between early postoperative complications and PMI. Method: In our hospital, 138 patients were included in the study retrospectively. The patients were divided into 2 groups: Group 1 (on-pump) with 80 patients (22 females, 58 males, mean age 61.54 +/- 8.68) and Group 2 (off-pump) with 58 patients (15 females, 43 males, mean age 61.34 +/- 10.04). In biochemical analysis, hemoglobin, platelet, white blood cell, and MPV values of the patients were evaluated in the biochemistry laboratory of our hospital with the blood taken preoperatively from the forearm veins and postoperatively on the first, third, and seventh days and, on average, after the first month. Results: There was a statistically significant difference between postoperative first day thrombocyte (K/mu L) (P = .005), postoperative first day PMI (P = .014), postoperative first day leukocyte (K/mu L) (P = .001), postoperative first day Hb (g/dL) (P = .001), postoperative third day thrombocyte (K/mu L) (P = .003), postoperative third day PMI (P = .031), postoperative third day leukocyte (K/mu L) (P = .004), and postoperative seventh day leukocyte (K/mu L) (P = .002). There was no meaningful relationship between PMI and early postoperative complications. Conclusion: We think PMI is a more valuable indicator than MPV as an inflammation marker in cardiac surgery. In our opinion, PMI is a cheap and valuable inflammation marker that can be used in coronary surgery that can be obtained from routine hemogram test and can easily be evaluated.