| dc.contributor.author | Korcan, Safiye Elif | |
| dc.contributor.author | Aksoy, Bilgi | |
| dc.contributor.author | Erdoğmuş, Sevim | |
| dc.contributor.author | Ulukütük, Sevgi | |
| dc.date.accessioned | 2025-12-28T16:54:01Z | |
| dc.date.available | 2025-12-28T16:54:01Z | |
| dc.date.issued | 2018 | |
| dc.identifier.issn | 2149-3367 | |
| dc.identifier.uri | https://doi.org/10.5578/fmbd.67554 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/tr/yayin/detay/307592 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12933/3275 | |
| dc.description.abstract | In this study, antimicrobial activity, antioxidant capacity of Melissa officinalis leaf extracts and DNAprotective effect aginst H 2 O 2 -induced oxidative damage were investigated. DNA protective effect ofMelissa officinalis's leaf extract from oxidative stress was determined by using yeast comet assay. Thecomet assay, applied on Saccharomyces cerevisiae BY4741. We observed that DNA damage decreasedin a dose dependent manner in experiments of preincubation and simultaneous incubation with theextract upon oxidative shock. Results indicated that Melissa officinalis's methanolic leaf extract protectthe DNA against the damaging effect of hydrogen peroxide. Also we indicated that the antimicrobialeffects of Melissa officinalis's extract on the different microorganisms. Extract of Melissa officinalisshowed antimicrobial effect on all test test microorganisms. | |
| dc.language.iso | en | |
| dc.relation.ispartof | Afyon Kocatepe Üniversitesi Fen ve Mühendislik Bilimleri Dergisi | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Biyoloji | |
| dc.subject | Mantar Bilimi | |
| dc.subject | Kimya | |
| dc.subject | Tıbbi | |
| dc.title | Investigation of Antimicrobial Activity and DNA Protective Capacity of Melissa officinalis Extracts | |
| dc.type | Article | |
| dc.department | Uşak University, Health Services Vocational School, Uşak, Turkey,Afyon Kocatepe University, Faculty of Arts and Science, Department of Molecular Biology and Genetics, Afyonkarahisar, Turkey,Afyonkarahisar Health Sciences University, Şuhut Health Service Vocational School, Afyonkarahisar, Turkey,Afyon Kocatepe Üniversitesi, Fen Bilimleri ve Edebiyatları, Moleküler Biyoloji ve Genetik Bölümü, Afyon, Türkiye | |
| dc.identifier.doi | 10.5578/fmbd.67554 | |
| dc.identifier.volume | 18 | |
| dc.identifier.issue | 3 | |
| dc.identifier.startpage | 757 | |
| dc.identifier.endpage | 762 | |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.department-temp | Afyonkarahisar Sağlık Bilimleri Üniversitesi | |
| dc.identifier.trdizinid | 307592 | |
| dc.indekslendigikaynak | TR-Dizin | |
| dc.snmz | KA_TR-Dizin_20251227 | |
