Relationship between HbA1c levels and thickness of carotid intima media in prediabetic and diabetic patients

Abstract

Objective In this study, it was shown that cardiovascular risk can be reduced by controlling risk factors, and this can be achieved by measuring the carotid intima-media thickness (CIMT) and performing follow-up. An increase in atherosclerosis and cardiovascular risk factors is seen in the prediabetic stage, and CIMT measurement may help in preventing complications before developing diabetes and inflammatory processes. Method Total 89 patients and 40 healthy controls were analyzed to determine the relationship between their mean HbA1c levels, laboratory data, and CIMT in patients with identified chronic diseases. Results No significant correlation was noted between the mean HbA1c and right and left CIMT in patients with diabetes mellitus. In the prediabetic patient group, the a weak positive and significant correlation was found between mean HbA1c and bilateral CIMT analysis. Conclusion In conclusion, the risk of atherosclerosis and cardiovascular complications is increased in the prediabetic stage and non-invasive evaluation with treatment and follow-up may prevent complications, especially cardiovascular ones, in the diabetic stage. © 2025 The Authors.