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Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study

dc.contributor.authorUysal, Mukremin
dc.contributor.authorSaglam, Sezer
dc.contributor.authorBeypinar, Ismail
dc.contributor.authorSaglam, Esra Kaytan
dc.contributor.authorMammadov, Elkhan
dc.contributor.authorOcak, Birol
dc.contributor.authorAybi, Ozge
dc.date.accessioned2025-12-28T16:40:07Z
dc.date.available2025-12-28T16:40:07Z
dc.date.issued2025
dc.identifier.issn0735-7907
dc.identifier.issn1532-4192
dc.identifier.urihttps://doi.org/10.1080/07357907.2025.2595536
dc.identifier.urihttps://hdl.handle.net/20.500.12933/2402
dc.description.abstractThe goal of this study was to look at the long-term survival outcomes and clinical characteristics of stage II/III locally advanced rectal cancer (LARC) patients who acquired pathological complete response (pCR) following neoadjuvant chemoradiotherapy (NCRT). The clinicopathological characteristics and treatment details of 277 LARC patients with pCR, relapse-free survival (RFS), overall survival (OS), and locoregional and systemic recurrence rates, were assessed. The 5-year RFS and OS rates were 85.6% and 90.9%. The rates of local and systemic recurrence were 3.6% and 7.9%. Our study confirmed the favorable results in survival in patients with LARC who achieved pCR
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCancer Investigation
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDisease-free survival
dc.subjectLocal recurrence
dc.subjectLocal advanced rectal cancer
dc.subjectNeoadjuvant chemoradiation
dc.subjectPathological complete response
dc.subjectOverall survival
dc.subjectSurgical outcome
dc.titleLong-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study
dc.typeArticle
dc.departmentAfyonkarahisar Sağlık Bilimleri Üniversitesi
dc.identifier.doi10.1080/07357907.2025.2595536
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.department-temp[Uysal, Mukremin] Antalya Bilim Univ, Medstar Antalya Hosp, Dept Med Oncol, Antalya, Turkiye; [Saglam, Sezer] Istanbul Bilim Univ, Dept Med Oncol, Istanbul, Turkiye; [Beypinar, Ismail] Afyonkarahisar Hlth Sci Univ, Dept Med Oncol, Afyonkarahisar, Turkiye; [Saglam, Esra Kaytan] Istanbul Univ, Dept Radiat Oncol, Istanbul, Turkiye; [Mammadov, Elkhan; Bilici, Ahmet] Medipol Univ, Dept Med Oncol, Istanbul, Turkiye; [Ocak, Birol] Uludag Univ, Dept Med Oncol, Bursa, Turkiye; [Aybi, Ozge; Kilickap, Saadettin] Hacettepe Univ, Canc Inst, Dept Med Oncol, Ankara, Turkiye; [Arikan, Rukiye; Alan, Ozkan] Marmara Univ, Sch Med, Dept Internal Med, Div Med Oncol, Istanbul, Turkiye; [Ergen, Sefika Arzu; Oksuz, Didem Colpan] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Radiat Oncol, Istanbul, Turkiye; [Gursoy, Pinar; Karabulut, Bulent] Ege Univ, Sch Med, Dept Internal Med, Div Med Oncol, Izmir, Turkiye; [Sakin, Abdullah] Yuzuncu Yil Univ, Fac Med, Dept Med Oncol, Van, Turkiye; [Kaya, Vildan] Medstar Antalya Hosp, Dept Radiat Oncol, Antalya, Turkiye; [Ozden, Ercan] Kocaeli Univ, Sch Med, Dept Med Oncol, Kocaeli, Turkiye; [Eren, Tulay] Diskapi Yildirim Beyazit Training & Res Hosp, Dept Med Oncol, Ankara, Turkiye; [Demiray, Atike Gokcen] Pamukkale
dc.identifier.pmid41347635
dc.identifier.scopus2-s2.0-105024909531
dc.identifier.scopusqualityN/A
dc.identifier.wosWOS:001631349200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.snmzKA_WoS_20251227


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