Comparison of Laparotomy and Laparoscopy for the Management of Endometrioid Endometrial Cancer with Cervical Involvement

Abstract

AimWe aimed to compare overall survival (OS) and progression-free survival (PFS) between patients treated with laparoscopy and laparotomy for endometrioid endometrial cancer (EEC) with cervical involvement.MethodsA total of 41 patients with EEC with cervical involvement were included in the study. The exclusion criteria were non-endometriod type endometrial cancer in the postoperative pathology report results, synchronous tumor or stage I endometrial cancer. Additionally, stage III and stage IV patients without cervical involvement were excluded. Participants were categorized into two groups, namely group 1 (21 patients who underwent laparotomy) and group 2 (20 patients who underwent laparoscopic surgery).Results5-year OS of EEC with cervical involvement was 61%, 52.4% in group 1 and 70% in group 2 (p = 0.417). Recurrence was detected in 7 patients. 5-year PFS of EEC with cervical involvement was 82.9%, 85.7% in group 1 and 80% in group 2 (p = 0.704). No significant difference was detected in terms of recurrence between the two groups (p = 0.840).ConclusionEEC represents the most common endometrial cancer subgroup and has a favorable prognosis. In this study, although our patient number was small, we compared laparoscopy and laparotomy in the treatment of EEC with cervical involvement and no statistical difference was found.