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dc.contributor.authorSarıkürkçü, Cengiz
dc.contributor.authorHanine, Hafida
dc.contributor.authorSarıkürkçü, Rabia Büşra
dc.contributor.authorSarıkürkçü, Rıfat Tayyib
dc.contributor.authorAmarowicz, Ryszard
dc.description.abstractCurrently, there is much interest in using the active compounds that exist in plants as natural treatments. The pharmaceutical industry is also looking for novel chemical compounds from natural sources that do not have side effects. The purpose of this study was to identify the antioxidant and enzymatic inhibition activities of different extracts (ethyl acetate, methanol and water) of Micromeria myrtifolia from Turkey. The phenolic constituents in the extracts were also identified using liquid chromatography–electrospray tandem mass spectrometry. The methanol and water extracts were rich in rosmarinic, syringic, chlorogenic, caffeic, and protocatechuic acids, while rosmarinic acid and apigenin were the main compounds in the ethyl acetate extract. Hence, the water extract showed the highest antioxidant activity and total phenol and flavonoid contents, followed by those of the methanol extract. However, inhibition of ?-amylase and tyrosinase was the most efficient in the methanol extract. The results of this study demonstrate that M. myrtifolia has significant potential as an antioxidant and inhibitor of tyrosinase and ?-amylase. Consequently, it could be considered a valuable resource for the food and cosmetics industries. © 2019 Elsevier B.V.en_US
dc.description.sponsorshipThe authors thank Dr. Olcay Ceylan for his contributions to the identification and collection of the plant used in this study.en_US
dc.publisherElsevier B.V.en_US
dc.subjectEnzyme inhibitionen_US
dc.subjectMicromeria myrtifoliaen_US
dc.subjectPhenolic profileen_US
dc.subjectRadical scavengingen_US
dc.subjectRosmarinic aciden_US
dc.titleMicromeria myrtifolia: The influence of the extracting solvents on phenolic composition and biological activityen_US
dc.departmentAFSÜ, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü
dc.contributor.institutionauthorSarıkürkçü, Cengiz
dc.relation.journalIndustrial Crops and Productsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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