Evaluation of effectiveness of the containing energized oxygen molecules herbal product on the wound healing
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info:eu-repo/semantics/openAccessTarih
2023Yazar
Okumuş, NurullahErdoğmuş, Sevim Feyza
Erdal Altıntaş, Özlem
Demirel, Hasan Hüseyin
Çelik, Sefa
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In recent years, the interest in herbal medicinal products has been increasing with the development of advanced formulation technologies related to the use of the medicinal and aromatic plants. These developed products are used to treat wounds and burns quickly and effectively. In this study, the effectiveness of containing energized oxygen molecules herbal product on wound healing was evaluated by in vitro and in vivo studies for the first time. Within the scope of the study, the biological activities of Hypericum perforatum L. medicinal oil, energized oxygen molecules base were determined. Results of this study showed that the base containing energized oxygen molecules and the medicinal oil of Hypericum perforatum L. had antimicrobial activity on pathogen test microorganisms and did not have a toxic effect on human dermal fibroblast cells. It has been determined that the herbal product containing energized oxygen molecule is effective in second degree deep burns. It is thought that the wound-healing effect of the product is realized thanks to its antimicrobial, antifungal, antioxidant and cell proliferation-increasing effect. In line with future clinical studies, the product has the potential to be used in the treatment of second-degree burns.