Advanced Search

Show simple item record

dc.contributor.authorPalandökenlier İbili, Aysel Burcu
dc.contributor.authorSelver Eklioğlu, Beray
dc.contributor.authorAtabek, Mehmet Emre
dc.identifier.citationIbili, A. B. P., Eklioglu, B. S., & Atabek, M. E. (2020). General properties of autoimmune thyroid diseases and associated morbidities. Journal of Pediatric Endocrinology and Metabolism, 33(4), 509-515.en_US
dc.description.abstractAutoimmune thyroid diseases (ATDs) can be classified into two basic diseases: Graves' disease (GD) and Hashimoto's thyroiditis (HT). Here, we review the effectiveness of laboratory and imaging methods used for the early diagnosis of ATD and draw attention to methods that may improve screening. Retrospective data of 142 patients diagnosed with ATD between January 2010 and December 2015 at our paediatric endocrinology clinic were used. Sociodemographic characteristics, clinical findings, treatments and follow-up data of patients were statistically evaluated. Of the ATD cases, 81% (n = 115) were female. The median age was 12.5 ± 3.5 (range 1-17) years and 91% (n = 129) of patients were in puberty. There was a significant positive correlation between the height (standard deviation score) and follow-up time for patients with HT (r = 0.156, p < 0.01). Thyroglobulin antibody (TgAb) positivity was found in 75% (45/60) of females with a positive maternal ATD history (p = 0.045). Thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4) values were significantly altered during the treatment follow-up period in female patients with GD and HT, while only fT4 values were found to be significantly altered in boys with HT. Although GD and HT have similar mechanisms, they differ in terms of treatment duration and remission and relapse frequencies. Ultrasonography (USG) screening is a non-invasive procedure that is suitable for all patients with ATD. Based on our results, TgAb could be useful in the screening of girls with a history of maternal ATD. © 2020 2020 Walter de Gruyter GmbH, Berlin/Boston.en_US
dc.publisherDe Gruyteren_US
dc.subjectAutoimmune thyroiden_US
dc.titleGeneral properties of autoimmune thyroid diseases and associated morbiditiesen_US
dc.departmentAFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.contributor.institutionauthorPalandökenlier İbili, Aysel Burcu
dc.relation.journalJournal of Pediatric Endocrinology and Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record