Do mydriatics effect serous pigment epithelial detachment elevation? A case report on central serous chorioretinopathy

Abstract

This report aimed to determine if pupil-dilating eye drops (mydriatics) affected serous pigment epithelial detachment elevation in an eye with central serous chorioretinopathy using spectral domain-optical coherence tomography. A 47-year-old man presented to our clinic with metamorphopsia in his right eye, which had best corrected visual acuity of 20/20. Spectral domain-optical coherence tomography revealed minimal subretinal fluid and serous pigment epithelial detachment. During the follow-up examination after the final diagnosis of central serous chorioretinopathy and serous pigment epithelial detachment, different pigment epithelial detachment elevations on optical coherence tomography images before and after pupil dilation were found incidentally. These elevations were re-measured separately on different days before and after pupil dilation with 2.5% phenylephrine and 1% tropicamide to determine if this was a mydriatic-induced increase in pigment epithelial detachment elevation, which was eventually found to be the case. Mydriatics appeared to affect pigment epithelial detachment elevation in central serous chorioretinopathy. A thorough consideration of pre- dilation ocular examination and imaging data in central serous chorioretinopathy may be valuable.