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dc.contributor.authorKırkan, Bülent
dc.contributor.authorSarıkürkçü, Cengiz
dc.contributor.authorŞıhoğlu Tepe, Arzuhan
dc.date.accessioned2022-06-09T09:37:16Z
dc.date.available2022-06-09T09:37:16Z
dc.date.issued12.02.2022en_US
dc.identifier.issn2069-5837
dc.identifier.urihttps://doi.org/10.33263/BRIAC131.088
dc.identifier.urihttps://hdl.handle.net/20.500.12933/1141
dc.description.abstractOnosma species have been used by the public for centuries to treat various diseases. This study aimed to analyze the chemical composition, antioxidant, and enzyme inhibitory activity potentials of the methanol extracts of O. cappadocica and O. rutilum, endemic to Turkish flora. The chemical compositions of the extracts were determined by using spectrophotometric and chromatographic methods. The biological activities of the extracts were determined by using antioxidant and enzyme inhibitory test systems. It was determined that the extracts contain high amounts of hesperidin, hyperoside, and rosmarinic acid. While O. rutilum exhibited higher activity in phosphomolybdenum, ABTS radical scavenging and ferrous ion chelating assays, reducing power, and DPPH radical scavenging tests resulted in the superiority of O. cappadocica. O. rutilum exhibited higher inhibition activity on all enzymes (acetylcholinesterase, butyrylcholinesterase, tyrosinase, and a-amylase), except for a-glucosidase. It was concluded that the extracts in question could be used as alternative agents in the food, cosmetic and medical industries due to their antioxidant and enzyme inhibitory activities. © 2022 by the authors.en_US
dc.language.isoengen_US
dc.publisherAMG Transcend Associationen_US
dc.relation.isversionof10.33263/BRIAC131.088en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOnosma cappadocicaen_US
dc.subjectOnosma rutilumen_US
dc.subjectAntioxidanten_US
dc.subjectEnzyme inhibitoryen_US
dc.subjectChemical compositionen_US
dc.titlePhytochemical Analysis and Biological Evaluation of Two Endemic Onosma Species (Onosma cappadocica and O. rutilum)en_US
dc.typearticleen_US
dc.authorid0000-0001-5094-2520en_US
dc.departmentAFSÜ, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.contributor.institutionauthorSarıkürkçü, Cengiz
dc.identifier.volume13en_US
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.endpage10en_US
dc.relation.journalBiointerface Research in Applied Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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