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dc.contributor.authorSarıtaş, Zülfükar Kadir
dc.contributor.authorKorkmaz, Musa
dc.contributor.authorDemirel, Hasan Hüseyin
dc.contributor.authorBülbül, Aziz
dc.contributor.authorSarıtaş, Tuba Berra
dc.contributor.authorGörücü, Fatma
dc.contributor.authorKoç, Yusuf
dc.date.accessioned2022-05-23T07:53:30Z
dc.date.available2022-05-23T07:53:30Z
dc.date.issued2022en_US
dc.identifier.citationSARITAŞ, Z., Korkmaz, M., DEMİREL, H. H., BÜLBÜL, A., SARITAŞ, T. B., GÖRÜCÜ, F., & Yusuf, K. O. Ç. (2021). Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 69(1), 91-97.en_US
dc.identifier.issn1308-2817
dc.identifier.urihttps://doi.org/10.33988/auvfd.834703
dc.identifier.urihttps://hdl.handle.net/20.500.12933/1050
dc.description.abstractThis study was investigated the wound healing effect of Anzer origin propolis specimens on rats’ experimental intestinal incisions. Thirty-four male Wistar albino rats have been divided into five groups, weighing 250-300 gr. Water solution of Anzer propolis (PW3 [n=6], PW7 [n=6]) or ethanolic solution of Anzer propolis (PE3 [n=6], PE7 [n=6]) were administered. Control groups (K3 [n=5], K7 [n=5]) received no treatment. The surgical procedure (day 0) consisted of a laparotomy under general anesthesia, during which the colon was incised and repaired with sutures. The Anzer propolis specimen diluted with physiologic saline was administered by gavage (100 mg/kg/day) for 3 and 7 days before and after surgery to PW3 and PW7 groups. Ethanol dissolved Anzer propolis was administered by gavage (100 mg/kg/day) for 3 and 7 days before and after surgery to PE3 and PE7. Experimental animals have been humanly euthanized on the 3rd and 7th days for biochemical and histopathological evaluations. Serum total oxidant status, total antioxidant status, interleukin-1, interleukin-6, tumor necrosis factor-alpha, myeloperoxidase, hydroxyproline and nitric oxide, levels were measured by ELISA. The incision line sampled to evaluate inflammatory cells, fibroblastic activity, neovascularization, and collagen level. The study indicates that the ethanolic Anzer propolis solution's oral administration has a beneficial effect on intestinal wound healing for seven days pre-and postoperatively (PE7).en_US
dc.language.isoengen_US
dc.publisherANKARA UNIV PRESSen_US
dc.relation.isversionof10.33988/auvfd.834703en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnzer Propolisen_US
dc.subjectIntestinal incision wound healingen_US
dc.subjectRaten_US
dc.subjectTotal antioxidant statusen_US
dc.subjectTotal oxidant statusen_US
dc.titleWound healing effect of Anzer origin propolis specimens on rats’ intestinal incisionen_US
dc.typearticleen_US
dc.authorid0000-0002-3206-6851en_US
dc.departmentAFSÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalıen_US
dc.contributor.institutionauthorSarıtaş, Tuba Berra
dc.identifier.volume69en_US
dc.identifier.issue1en_US
dc.identifier.startpage91en_US
dc.identifier.endpage97en_US
dc.relation.journalAnkara Üniversitesi Veteriner Fakültesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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