Ara
Toplam kayıt 171, listelenen: 81-90
Synthesis, antifungal activities, molecular docking and molecular dynamic studies of novel quinoxaline-triazole compounds
(D.C. : American Chemical Society, 2023)
Uncontrolled use of antifungal drugs affects the development of resistance to existing drugs. Azole antifungals constitute a large part of antifungal therapy. Therefore, there is a need for new azole antifungals. Within ...
Evaluation of MicroRNAs in Pediatric Epilepsy
(Turkey : AVES, 2023)
Objective: The pathophysiology of epilepsy remains unknown. Recent research has shown that microRNA expression changes in epileptic adults. In the present work, we aimed to identify serum microRNA expression in drug-responsive ...
Determination of PDK1, SLC2A1, EGFR, PTEN, CD276 gene expression levels and IDH1 gene R132H polymorphism in brain tumor tissues
(Turkey : Turkish Neurosurgi[c]al Society, 2023)
Aim: This study aimed to determine IDH1 R132H codon and the mRNA levels of PDK1, SLC2A1, EGFR, PTEN, and CD276 genes in brain tumors.
Material and methods: This study included 15 brain tumor tissues [pituitary adenoma ...
Regulation of tight junction proteins and cell death by peroxisome proliferator-activated receptor γ agonist in brainstem of hypertensive rats
(Springer Verlag, 2023)
The decrease in tight junction proteins and their adapter proteins in the hypertensive brain is remarkable. Here, we aimed to investigate tight junction proteins and peroxisome proliferator-activated receptor (PPARγ) ...
Brown tumour of mandible in association with tertiary hyperparathyroidism: A rare case report
(Elsevier, 2023)
Hyperparathyroidism (HPT) is a disease characterised by the parathyroid glands secreting excessive amounts of parathyroid hormone
because of a defect in the secretion mechanism of parathyroid hormone.
Because of this, ...
Nano solid phase micro membrane tip and electrochemical methods for vanillin analysis in chocolate samples
(Academic Press, 2023)
A polymer-based nanosensor and electrochemical methods were developed for the quantitative analysis of vanillin. The sample preparation was done using nano solid phase micro membrane tip extraction (NSPMMTE). A novel ...
Influence of access cavity design on calcium hydroxide removal using different cleaning protocols: A confocal laser scanning microscopy study
(Korean Academy of Conservative Dentistry, 2023)
Objectives: The purpose of this study was to evaluate the influence of endodontic access cavities design on the removal of calcium hydroxide medication of the apical third of mandibular incisor root canal walls and dentinal ...
Synthesis of imidazole-2,3-dihydrothiazole compounds as VEGFR-2 inhibitors and their support with in silico studies
(Hoboken, NJ : Verlag Helvetica Chimica Acta, 2023)
In this study, 12 novel 2-((1-(4-(1H-imidazol-1-yl)phenyl)ethylidene)hydrazineylidene)-3-ethyl-4-(substitutephenyl)-2,3-dihydrothiazole derivatives were obtained. Among these compounds, 2-((1-(4-(1H-imidazol-1-yl)phenyl) ...
Clinical and genetic evaluations of rare childhood epilepsies in Turkey's national cohort
([Hoboken], 2023)
Abstract
Objective: As new-generation sequencing methods develop, rare epilepsy is increasing and burdening national health systems-community building among rare epilepsies fuels collaboration, research, and resource ...
Synthesis and anticancer activities of pyrazole-thiadiazole-based EGFR inhibitors
(American Chemical Society, 2023)
Abstract
Lung cancer is one of the most common cancer types of cancer with the highest mortality rates. However, while epidermal growth factor receptor (EGFR) is an important parameter for lung cancer, EGFR inhibitors ...