ORCID "0000-0002-8550-793X" Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed için listeleme
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Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region-associated protein synthesis and TLR4/NF-κB signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna (Wiley-Blackwell, 2022)In this study, the protective effect of melatonin was investigated in lipopolysaccharide induced sepsis model. Twenty-eight rats were randomly divided: Control, Melatonin, LPS and LPS + Melatonin. After LPS application, ... -
Determination of Rutin's antitumoral effect on EAC solid tumor by AgNOR count and PI3K/AKT/mTOR signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Arıkan Söylemez, Evrim Suna; Nisari, Mehtap; Farooqi, Ammad Ahmed (Springer, 2023)Rutin is one of the flavonoids found in fruits and vegetables. The PI3K/AKT/mTOR signaling pathway is critical for the life cycle at the cellular level. In current study, we purposed to demonstrate the antitumoral effect ... -
Effect of labor pain on placental gene expressions
Arıkan Söylemez, Evrim Suna; Arıöz, Dağıstan Tolga; Chkhikvadze, Mariam (Holistence Publications, 2023)A close relationship between labor and the placenta is known. The study of gene expression profiles describing the effects of labor on placental tissue has accelerated in recent years. This study aims to compare the ... -
Effect of Pethidine Hydrochloride on the Development of Neural Tube: A Genetic Analysis Study in a Chick Embryo Model
Rakip, Usame; Bilir, Abdulkadir; Arıkan, Evrim Suna (Elsevier, 19.03.2021)Background Neural tube defects are among the most frequent congenital abnormalities of the central nervous system. Progression of neural tube deficits is affected by hereditary predilection and environmental determinants. ... -
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-κB/TNF-α signaling pathways: Experimental study
Okan, Aslı; Doğanyiğit, Züleyha; Yılmaz, Seher; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna; Attar, Rukset (Wiley-Blackwell, 2023)The development and progression of sepsis are multifactorial and influence the immunological, endocrine, and cardiovascular systems of the body. Our knowledge of the key mechanisms involved in the pathogenesis of sepsis ... -
Investigation of the expression levels of CDH1, FHIT, PTEN, and TTPAL genes in colorectal tumors
Arıkan Söylemez, Evrim Suna; Söylemez, Zafer; Çilekar, Murat; Arıkan, Yüksel; Tokyol, Çiğdem; Kenger, İbrahim Halil; Solak, Mustafa (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL, 2022)Background/aim: The main aim of the study is to assess expression levels of CDH1, FHIT, PTEN, and TTPAL genes in tumors and peripheral bloods of colorectal cancer patients in staged I-IV. Materials and methods: Gene ... -
Investigation of the expression levels of CPEB4, APC, TRIP13, EIF2S3, EIF4A1, IFNg,PIK3CA and CTNNB1 genes in different stage colorectal tumors
Söylemez, Zafer; Arıkan, Evrim Suna; Solak, Mustafa; Arıkan, Yüksel; Tokyol, Çiğdem; Şeker, Hüseyin (Turkiye Klinikleri, 2021)Background/aim: The aim of the study is to assess expression levels of CPEB4, APC, TRIP13, EIF2S3, EIF4A1, IFNg, PIK3CA and CTNNB1 genes in tumors and peripheral bloods of colorectal cancer patients in stages I-IV. Materials ...