Browsing by Author "Doğanyiğit, Züleyha"
Now showing items 1-4 of 4
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Detection of antitumoral effects of quercetin through protein synthesis associated with argyrophilic nucleolar-regulating region
Yılmaz, Seher; Aslan, Esra; Doğanyiğit, Züleyha (SAGE Publications Ltd, 2021)Quercetin is a natural flavonoid with potential anticancer properties without significant cytotoxicity in normal tissues. However, the effects of quercetin on Ehrlich ascites carcinoma (EAC) have not yet been clarified. ... -
Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region-associated protein synthesis and TLR4/NF-κB signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna (Wiley-Blackwell, 2022)In this study, the protective effect of melatonin was investigated in lipopolysaccharide induced sepsis model. Twenty-eight rats were randomly divided: Control, Melatonin, LPS and LPS + Melatonin. After LPS application, ... -
Determination of Rutin's antitumoral effect on EAC solid tumor by AgNOR count and PI3K/AKT/mTOR signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Arıkan Söylemez, Evrim Suna; Nisari, Mehtap; Farooqi, Ammad Ahmed (Springer, 2023)Rutin is one of the flavonoids found in fruits and vegetables. The PI3K/AKT/mTOR signaling pathway is critical for the life cycle at the cellular level. In current study, we purposed to demonstrate the antitumoral effect ... -
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-κB/TNF-α signaling pathways: Experimental study
Okan, Aslı; Doğanyiğit, Züleyha; Yılmaz, Seher; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna; Attar, Rukset (Wiley-Blackwell, 2023)The development and progression of sepsis are multifactorial and influence the immunological, endocrine, and cardiovascular systems of the body. Our knowledge of the key mechanisms involved in the pathogenesis of sepsis ...
