Yazar "Yılmaz, Seher" için listeleme
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Antioxidant role of melatonin against nicotine's teratogenic effects on embryonic bone development
Yılmaz, Halil; Ertekin, Tolga; Atay, Emre; Nisari, Mehtap; Susar Güler, Hatice; Al, Özge; Payas, Ahmet; Yılmaz, Seher (Mashhad Univ Med Sciences, 2018)Objective(s): This study investigated the possible effects of low (3 mg/kg) and high (6 mg/kg) doses of nicotine on the skeletal development of rat fetuses by the double staining method and the protective role of melatonin ... -
Detection of antitumoral effects of quercetin through protein synthesis associated with argyrophilic nucleolar-regulating region
Yılmaz, Seher; Aslan, Esra; Doğanyiğit, Züleyha (SAGE Publications Ltd, 2021)Quercetin is a natural flavonoid with potential anticancer properties without significant cytotoxicity in normal tissues. However, the effects of quercetin on Ehrlich ascites carcinoma (EAC) have not yet been clarified. ... -
Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region-associated protein synthesis and TLR4/NF-κB signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna (Wiley-Blackwell, 2022)In this study, the protective effect of melatonin was investigated in lipopolysaccharide induced sepsis model. Twenty-eight rats were randomly divided: Control, Melatonin, LPS and LPS + Melatonin. After LPS application, ... -
Determination of Rutin's antitumoral effect on EAC solid tumor by AgNOR count and PI3K/AKT/mTOR signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Arıkan Söylemez, Evrim Suna; Nisari, Mehtap; Farooqi, Ammad Ahmed (Springer, 2023)Rutin is one of the flavonoids found in fruits and vegetables. The PI3K/AKT/mTOR signaling pathway is critical for the life cycle at the cellular level. In current study, we purposed to demonstrate the antitumoral effect ... -
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-κB/TNF-α signaling pathways: Experimental study
Okan, Aslı; Doğanyiğit, Züleyha; Yılmaz, Seher; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna; Attar, Rukset (Wiley-Blackwell, 2023)The development and progression of sepsis are multifactorial and influence the immunological, endocrine, and cardiovascular systems of the body. Our knowledge of the key mechanisms involved in the pathogenesis of sepsis ... -
The investigation of the antitumoral effect of Cornus mas L in mice with ehrlich solid tumor
Yılmaz, Seher; Alpa, Şerife; Göçmen, Ayşe Yeşim; Ülger, Harun; Aslan, Esra; Yay, Arzu Hanım; Ertekin, Tolga; Nisari, Mehtap; Yalçın, Betül (Comenius University, 2020)AIM: Cornus mas L is commonly used due to its anti-inflammatory, anti-carcinogenic and anti-oxidant properties. In the study, the effects of C. mas L extract on a solid tumor were examined in the Ehrlich solid tumor model ... -
The protective role of melatonin against the effects of different doses of caffeine on the fetus
Yılmaz, Seher; Göçmen, Ayşe Yeşim; Arıkan, Evrim Suna; Akyüz, Enes; Tokpınar, Adem; Nisari, Mehtap; Unur, Erdoğan; Yay, Arzu Hanım; Yalçın, Betül; Yılmaz, Halil; Ertekin, Tolga; Güler, Hatice; Sabitaliyevich, Uteuliyev Yerzhan (C M B Assoc, 2020)Skeletal system and some organs development changes in rat fetuses with 30 and 60 mg/kg caffeine and melatonin's (10 mg/kg) protective role against rat fetuses were investigated. Groups (n = 4) were formed as Control, LDC, ... -
The protective role of vitamin E against teratogenic effects of nicotine on embryonic bone development
Susar, Hatice; Aycan, Kenan; Yılmaz, Seher; Nisari, Mehtap; Ertekin, Tolga; Al, Özge; Atay, Emre; Yılmaz, Halil; Güçlü Ekinci, Hilal Kübra (Effect Publishing Agency ( EPA ), 2022)Aim: According to World Health Organization data, around 1.5 billion people in the world use tobacco products. Nicotine, the most common use of tobacco, is the main psychoactive substance that causes addiction. Exposure ...
