Yazar "Vurmaz, Ayhan" için listeleme
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Antioxidant effects of piperine in in-vivo chick embryo cataract model induced by steroids
Vurmaz, Ayhan; Duman, Reşat; Sabaner, Mehmet Cem; Ertekin, Tolga; Bilir, Abdulkadir (Taylor & Francis Ltd, 2019)Purpose: The etiopathogenesis of steroid-induced cataracts is unknown. One hypothesis is that the higher reactive oxygen species (ROS) levels play an important role in the pathogenesis of several disorders, including the ... -
Antioxidant effects of piperine on steroid-induced hepatotoxicity
Vurmaz, Ayhan; Atay, Emre (Verduci, 2021)OBJECTIVE: Glucocorticoids (GCs) are steroids that play an essential role in physiological processes and are valuable therapeutic agents against various diseases. The aim of our study was to evaluate the antioxidant effects ... -
Determination of experimentally given homocysteine causes to alzheimer-like dementia in rats on the basis of different parameters
Dosay Akbulut, Mine; Vurmaz, Ayhan (2019)Alzheimer’s disease (AD) is the most seen form of neurodegenerative disease with specific pathological findings like; senile plaques (CPs), synaptic loss, neurofibrillary tangles (NFTs) and neurodegeneration. Homocysteine ... -
Do SGLT2 inhibitors prevent preclinical diabetic retinopathy? A Prospective Pilot Optical Coherence Tomography Angiography Study
Sabaner, Mehmet Cem; Duman, R; Doğan, Mustafa; Akdoğan, Müberra; Vurmaz, Ayhan; Bozkurt, Erhan; Beysel, Selvihan (MASSON EDITEUR, 2021)Purpose: To evaluate the effects of metformin alone and combined treatment with metformin and an SGLT2 inhibitor on retinal microvascular morphology using optical coherence tomography angiography (OCTA) in isolated type 2 ... -
THE EFFECT OF BETAINE AND PIPERINE ON RATS WITH CREATED ALZHEIMER- LIKE DEMENTIA BY AF64A
OBJECTIVE: The great majority of dementia patients (about 60- 70%) su?er from Alzheimer disease (AD). The distinctive pathological signs of AD are senile plaques (SPs), neurofibrillary tangles (NFTS), synaptic loss and ... -
The Effect of Nasal Steroid and Antihistamine Use on Total Oxidative Stress and Antioxidant Status in the Treatment of Allergic Rhinitis
Kahveci, Orhan Kemal; Kuzu, Selçuk; Altıntaş, Mustafa; Vurmaz, Ayhan; Çelik, Sefa (SAGE Publications Inc., 2021)Introduction: The purpose of this study is to determine the post-treatment levels of total oxidant status (TOS) and total antioxidant status (TAS), that are increased due to pathophysiology, and to compare those with ... -
Effects of second-generation H1-antihistamine drugs on angiogenesis in in vivo chick chorioallantoic membrane model
Duman, Nilay; Duman, Reşat; Vurmaz, Ayhan (Informa Healthcare, 2022)Background: Literature on the effects of second-generation H1-antihistamines on angiogenesis is limited. Objectives: To investigate the effects of cetirizine, desloratadine, and rupatadine (second-generation H1-antihistamines ... -
Effects of topical prostaglandin drops on angiogenesis in an in ovo chick chorioallantoic membrane model
Sabaner, Mehmet Cem; Duman, Reşat; Vurmaz, Ayhan; Ertekin, Tolga (Taylor & Francis Ltd, 2021)Background: To investigate the effects of bimatoprost, latanoprost and travoprost on angiogenesis in the chick chorioallantoic membrane (CAM) model in ovo Materials and methods: Fifty fertilized specific-pathogen-free chick ... -
Effects of vitamin E in a glucocorticoid induced cataract model in chicken embryos
Vurmaz, Ayhan; Ertekin, Ayşe; Sabaner, Mehmet Cem; Atay, Emre; Bozkurt, Erhan; Bilir, Abdulkadir (Taylor & Francis Ltd, 2020)We investigated the antioxidant effects of vitamin E on a glucocorticoid (GC) induced model of cataracts in chick embryos. We used 70 fertilized eggs divided into seven groups as follows: phosphate-buffered saline (PBS) ... -
Evaluation of vitamin D levels according to season and age
Vurmaz, Ayhan; Köken, Tülay (2020)Low vitamin D levels have also been associated with many chronic diseases, including diabetes mellitus, hypertension, cancer, and autoimmune diseases. This study aimed to examine the 25-hydroxy vitamin D (25OH-D) level ... -
Farklı ısı derecelerinin kan hücrelerinin morfolojisi ve yaşam süresine olan etkisinin değerlendirilmesi
Erdem, Serpil; Tosun, Murat; Vurmaz, Ayhan; Köken, Tülay (2014)Amaç: Kandaki ısı değişikliklerinin kan hücrelerinde oluşturduğu morfolojik değişiklikleri incelemek apoptotik ölümlerini değerlendirmektir. Gereç ve Yöntem: Çalışmada yaşları 18-25 arasında değişen tamamen sağlıklı 6 kadın ... -
GRAVES HASTALARINDA KARDİYOVASKÜLER RİSK FAKTÖRÜ OLARAK: MPV VE RDW
Bozkurt, Erhan; Beysel, Selvihan; Hafızoğlu, Merve; Koca, Oğuzhan; Vurmaz, Ayhan; Gökaslan, Serkan (2020)AMAÇ: Bu çalışmada graves hastalarının sağlıklı kontrol grubuna göre ortalama trombosit hacmi (MPV) ve kırmızı kan hücresi dağılım genişliği (RDW) değerlerinin karşılaştırılması ve kardiyovasküler risk faktörleri ile ... -
Observation of the neuroprotective efficacy of vitamin K in a streptozocin-induced diabetes model in chick embryos
Vurmaz, Ayhan; Atay, Emre; Rakip, Usame; Koca, Tülay (NY : Wiley, 2023)Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia due to insulin deficiency and/or resistance. Vitamin K (VK) is a group of fat-soluble molecules, including naturally occurring vitamin K1 ... -
Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against ehrlich ascites carcinoma-bearing balb/c mice
Bozkurt, Erhan; Atay, Emre; Pektaş, Gökhan; Ertekin, Ayşe; Vurmaz, Ayhan; Korkmaz, Ömer Adil; Sadi, Gökhan; Aslan, Esra; Koca, Oğuz Han; Pektaş, Mehmet Bilgehan (Iranian Journal of Pharmaceutical Research, 2020)We investigated the potential influence of kefir-induced juglone and resveratrol fractions (JRK) against Ehrlich Ascites Carcinoma (EAC) bearing BALB/c male mice. Kefir yeast was grown in the cell culture supplemented with ... -
Prolidase activity and oxidative stress in benign, pre-malignant and malignant endometrial lesions
Köse, Mesut; Vurmaz, Ayhan; Çelik, Yasemin (Ayşe SURUÇ, 2023)OBJECTIVE: The present study aims to investigate the prolidase activity, total oxidant status (TOS) and total anti-oxidant status (TAS) in women who have been diagnosed with benign, pre-malignant and malignant endometrial ... -
Protective effects of different doses of ginsenoside-Rb1 experimental cataract model that in chick embryos
Kundakcı, Yunus Emre; Bilir, Abdulkadir; Atay, Emre; Vurmaz, Ayhan; Firat, Fatma; Arıkan, Evrim Suna (IRL Press, 2023)Purpose: There has been increased interest in phytochemical antioxidants to prevent protein damage and aggregate formation in cataract treatment. In this study, the protective effect of different doses of Rb1 (GRb1), one ... -
The Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure
Dural, İbrahim Etem; Onrat, Ersel; Çelik, Sefa; Vurmaz, Ayhan; Yalım, Zafer; Gökaslan, Serkan; Gökaslan, Çiğdem; Korucu, Cem; Aksu, Uğur (AVES Yayıncılık, 2022)Objective: Dietary recommendations, in addition to medications, have recently become important in the treatment of heart failure. Our study aimed to show the positive effects of both milk chocolate and dark chocolate on ...