Yazar "Tepe, Bektaş" için listeleme
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Astragalus gymnolobus, A. leporinus var. hirsutus, and A. onobrychis: Phytochemical analysis and biological activity
Sarıkürkçü, Cengiz; Şahinler, Saliha Şeyma; Tepe, Bektaş (Elsevier, 2020)Astragalus is a genus with many important medicinal plant species. The historical background of Astragalus species dates back to 2000-3000 years. In this study, it was aimed to investigate the phytochemical composition, ... -
Campanula macrostachya: biological activity and identification of phenolics using a liquid chromatography electrospray ionization tandem mass spectrometry system
Sarıkürkçü, Cengiz; Sarıkürkçü, Rıfat Tayyib; Tepe, Bektaş (Springer Heidelberg, 2021)It is known that some Campanula species are traditionally used because of their anti-allergic, spasmolytic, antiphlogistic, antioxidant, and antiviral properties. This study was designed to evaluate the phytochemical ... -
Can Acanthus spinosus be used as an alternative antioxidant and enzyme inhibitory agent?
Sarıkürkçü, Cengiz; Kırkan, Bülent; Şahinler, Saliha Şeyma; Tepe, Bektaş (Elsevier, 2022)Plant polyphenols attract researchers because of their bioactive properties. In this study, the chemical compositions and in vitro antioxidant and enzyme inhibitory activities of ethyl acetate (EtOAc), methanol (MeOH), and ... -
Chromatographic profile and antioxidant and enzyme inhibitory activity of Sideritis leptoclada: An endemic plant from Turkey
Sarıkürkçü, Cengiz; Özer, Mehmet Sabih; İstifli, Erman Salih; Şahinler, Saliha Şeyma; Tepe, Bektaş (Elsevier B.V., 2021)Sideritis species have been used for centuries for their antimicrobial, digestive, anti-ulcerogenic and anti-inflammatory properties. Therefore, in this study, it was aimed to evaluate the chemical composition, antioxidant ... -
Determination of the interaction between the receptor binding domain of 2019-nCoV spike protein, TMPRSS2, cathepsin B and cathepsin L, and glycosidic and aglycon forms of some flavonols
İstifli, Erman Salih; Şıhoğlu Tepe, Arzuhan; Netz, Paulo A.; Sarıkürkçü, Cengiz; Kılıç, İbrahim Halil; Tepe, Bektaş (Scientific and Technical Research Council of Turkey, 30.08.2021)The novel coronavirus (COVID-19, SARS-CoV-2) is a rapidly spreading disease with a high mortality. In this research, the interactions between specific flavonols and the 2019-nCoV receptor binding domain (RBD), transmembrane ... -
Element concentration, daily intake of elements, and health risk indices of wild mushrooms collected from Belgrad Forest and Ilgaz Mountain National Park (Turkey)
Keskin, Feyyaz; Sarıkürkçü, Cengiz; Akata, Ilgaz; Tepe, Bektaş (Springer, 13.05.2021)The aim of this study was to determine the element content of wild edible and inedible mushroom species (Agaricus campestris, Armillaria ostoyae, Boletus reticulatus, Bondarzewia mesenterica, Bovistella utriformis, ... -
Enzyme and biological activities of the water extracts from the plants aesculus hippocastanum, olea europaea and hypericum perforatum that are used as folk remedies in Turkey
Sarıkürkçü, Cengiz; Locatelli, Marcello; Tartaglia, Angela; Ferrone, Vincenzo; Juszczak, Aleksandra M.; Özer, Mehmet Sabih; Tepe, Bektaş; Tomczyk, Michał (MDPI AG, 2020)Phenolic compounds are secondary metabolites that are found ubiquitously in plants, fruits, and vegetables. Many studies have shown that regular consumption of these compounds could have a positive effect on our health. ... -
Evaluation of the metal concentrations of wild mushroom species with their health risk assessments
Sarıkürkçü, Cengiz; Yıldız, Dilek; Akata, Ilgaz; Tepe, Bektaş (Springer Heidelberg, 2021)The ability of mushrooms to accumulate heavy metals has increased concerns over their toxic effects on human health in recent years. The aim of this study was to determine the metal contents (Zn, Fe, Co, Mn, Cu, Pb, Ni, ... -
The importance of Lavandula stoechas L. in pharmacognosy and phytotherapy
Sahinler, Saliha Seyma; Sever Yılmaz, Betül; Sarıkürkçü, Cengiz; Tepe, Bektaş (İzzet KARA, 2022)Lavandula stoechas is distributed in Africa, Europe, and Asia continents, especially in the countries of Southern Europe and North Africa neighboring the Mediterranean. The use of L. stoechas, which has a cosmopolitan ... -
In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel coronavirus and cellular proteases and their pharmacokinetic properties
İstifli, Erman Salih; Netz, Paulo A.; Şıhoğlu Tepe, Arzuhan; Hüsunet, Mehmet Tahir; Sarıkürkçü, Cengiz; Tepe, Bektaş (Taylor & Francis Inc, 2020)Coronavirus Disease 2019 (COVID-19) has infected more than thirty five million people worldwide and caused nearly 1 million deaths as of October 2020. The microorganism causing COVID-19 was named as Severe Acute Respiratory ... -
Interaction of certain monoterpenoid hydrocarbons with the receptor binding domain of 2019 novel coronavirus (2019-nCoV), transmembrane serine protease 2 (TMPRSS2), cathepsin B, and cathepsin L (CatB/L) and their pharmacokinetic properties
İstifli, Erman Salih; Şıhoğlu Tepe, Arzuhan; Sarıkürkçü, Cengiz; Tepe, Bektaş (Tubitak Scientific & Technical Research Council Turkey, 2020)As of June 2020, the coronavirus disease 19 (COVID-19) caused by the 2019 new type coronavirus (2019-nCoV) infected more than 7,000,000 people worldwide and caused the death of more than 400,000 people. The aim of this ... -
LC-MS/MS analyses and biological activities of Onosma sintenisii and O. mutabile
Özer, Mehmet Sabih; Sencan, Kemal Erdem; Sarıkürkcü, Cengiz; Tepe, Bektaş (İzzet KARA, 2022)This study was aimed to investigate the chemical compositions, in vitro antioxidant and enzyme inhibitory activities of methanol extracts from O. sintenisii and O. mutabile. Spectrophotometric analyzes showed that the total ... -
Metal concentration and health risk assessment of eight Russula mushrooms collected from Kizilcahamam-Ankara, Turkey
Sarıkürkçü, Cengiz; Akata, Ilgaz; Tepe, Bektaş (Springer Heidelberg, 2021)The aim of this study was to determine the essential element (Zn, Ca, K, Fe, Na, and Mg), essential trace element (Co, Mn, Cr, and Cu), and non-essential element (Pb, Ni, and Cd) contents of eight different Russula species ... -
Metal concentration and health risk assessment of fifteen wild mushrooms collected from the Ankara University Campus (Turkey)
Sarıkürkçü, Cengiz; Sarıkürkçü, Rıfat Tayyib; Akata, Ilgaz; Tepe, Bektaş (Springer Heidelberg, 2020)The aim of this study is to analyze Fe, Mn, Cu, Zn, Co, Cd, Pb, and Ni contents of Cyclocybe cylindracea, Armillaria mellea, Bjerkandera adusta, Rheubarbariboletus armeniacus, Coprinellus disseminatus, C. micaceus, C. ... -
Metal concentration and health risk assessment of wild mushrooms collected from the Black Sea region of Turkey
Sarıkürkçü, Cengiz; Akata, Ilgaz; Güven, Gülsen; Tepe, Bektaş (Springer Heidelberg, 2020)Mushrooms are rich sources of organic nutrients (especially proteins). However, they can excessively accumulate metals in their fruiting bodies that pose a risk to human health. The aim of this study was the determination ... -
Metal concentrations of wild mushroom species collected from Belgrad forest (Istanbul, Turkey) with their health risk assessments
Keskin, Feyyaz; Sarıkürkçü, Cengiz; Akata, Ilgaz; Tepe, Bektaş (Springer Heidelberg, 2021)Wild edible mushrooms are very popular for both their flavors and nutritional values. However, some mushroom species can be harmful to human health as they accumulate some elements in excessive amounts. The aim of this ... -
Molecular interactions of some phenolics with 2019-nCoV and related pathway elements
İstifli, Erman Salih; Şıhoğlu Tepe, Arzuhan; Sarıkürkçü, Cengiz; Tepe, Bektaş (Pamukkale University, 2021)As of June 2021, the novel coronavirus disease (SARS-CoV-2) resulted in 180 million cases worldwide and resulted in the death of approximately 4 million people. However, an effective pharmaceutical with low side effects ... -
Onosma ambigens: Phytochemical composition, antioxidant and enzyme inhibitory activity
Sarıkürkçü, Cengiz; Şahinler, Saliha Şeyma; Ceylan, Olcay; Tepe, Bektaş (Elsevier, 2020)Due to their medical importance, the number of studies on the enlightenment of the biological activities of Onosma species has been increasing over the years. In this study, besides the phytochemical composition of Onosma ... -
Onosma aucheriana, O. frutescens, and O. sericea: Phytochemical profiling and biological activity
Sarıkürkçü, Cengiz; Şahinler, Saliha Şeyma; Tepe, Bektaş (Elsevier, 2020)It is known that Onosma species are frequently used in the treatment of various ailments such as bronchitis, strangury, leucoderma, abdominal pain and fever. The aim of this study was to investigate the antioxidant, ... -
Onosma gracilis (Trautv.) and O. oreodoxa (Boiss. & Heldr.): Phytochemistry, in silico docking, antioxidant and enzyme inhibitory activities
Baltacı, Nurnehir; Aydoğdu, Nida; Sarıkürkçü, Cengiz; Tepe, Bektaş (Elsevier B.V., 2021)In this study, it was aimed to determine the in vitro antioxidant and enzyme inhibitory activities of methanol (MeOH) extracts isolated from Onosma gracilis (Trautv.) and O. oreodoxa (Boiss. & Heldr.). O. oreodoxa was found ...
