Yazar "Sadi, Gökhan" için listeleme
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Differential expression and in silico functional analysis of plasma microRNAs in the pathogenesis of non-segmental vitiligo
Pektaş, Suzan Demir; Kara, Murat; Doğan, Gürsoy; Pektaş, Mehmet Bilgehan; Baloğlu, Mehmet Cengiz; Sadi, Gökhan (Medknow Publications, 2022)Vitiligo is a disease characterized by acquired depigmentation, white macules, and patches on the skin due to the dysfunction of epidermal melanocytes. In this study, we attempt to profile the microRNA (miRNA) expression ... -
Effects of Lactobacillus Plantarum and Lactobacillus Helveticus on Renal Insulin Signaling, Inflammatory Markers, and Glucose Transporters in High-Fructose-Fed Rats
Korkmaz, Ömer Adil; Şumlu, Esra; Koca, Halit Buğra; Pektaş, Mehmet Bilgehan; Kocabaş, Aytaç; Sadi, Gökhan; Akar, Fatma (Mdpi, 2019)Background and Objectives: The excess consumption of fructose in the diet may cause metabolic syndrome, which is associated with an increased risk of kidney disease. There is limited data on probiotic treatment in ... -
The inverse association between ANGPTL8 and PI3K-mTOR-PPAR gamma expressions in adipose tissue of high-fructose-fed rats: The modulatory effect of kefir
Akar, Fatma; Ceren, Güney; Özer, Hamdi Barbaros; Pektaş, Mehmet Bilgehan; Koca, Halit Buğra; Kocabaş, Aytaç; Sadi, Gökhan (İstanbul Üniversitesi, 2021)Background and Aims: The dietary high-fructose intake might be a risk factor for several metabolic diseases. Kefir, a fer mented milk product, has been proposed to have beneficial health effects. In this study, we aimed ... -
Kefir alters craniomandibular bone development in rats fed excess dose of high fructose corn syrup
Ekici, Ömer; Aslan, Esra; Güzel, Hilal; Korkmaz, Ömer Adil; Sadi, Gökhan; Gürol, Ahmet Muhtar; Boyacı, Mehmet Gazi; Pektaş, Mehmet Bilgehan (Springer, 06.10.2021)Introduction: Dietary high fructose corn syrup (HFCS) is involved in the pathogenesis of oral diseases as well as metabolic diseases. The aim of this study was to investigate the effects of HFCS-feeding on the craniomandibular ... -
Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity
Pektaş, Mehmet Bilgehan; Aslan, Esra; Güzel, Hilal; Korkmaz, Ömer Adil; Çeleğen, Kübra; Pektaş, Ayhan; Bostancı, Aykut; Sadi, Gökhan (De Gruyter, 03.05.2022)Objectives Phosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship ... -
Lactobacillus helveticus and Lactobacillus plantarum modulate renal antioxidant status in a rat model of fructose-induced metabolic syndrome
Korkmaz, Ömer Adil; Sadi, Gökhan; Kocabaş, Aytaç; Yıldırım, Onur Gökhan; Şumlu, Esra; Koca, Halit Buğra; Nalbantoğlu, Barbaros; Pektaş, Mehmet Bilgehan; Akar, Fatma (Inst Bioloska Istrazivanja Sinisa Stankovic, 2019)High dietary fructose intake causes a metabolic disorder and augments the risk of chronic kidney disease most likely due to oxidative stress. Probiotics could have antioxidant, antiinflammatory and immunoregulatory properties. ... -
Masseter muscle and gingival tissue inflammatory response following treatment with high-fructose corn syrup in rats: Anti-inflammatory and antioxidant effects of kefir
Ekici, Ömer; Aslan, Esra; Aladağ, Tuğçe; Güzel, Hilal; Korkmaz, Ömer Adil; Bostancı, Aykut; Sadi, Gökhan; Pektaş, Mehmet Bilgehan (Wiley, 2021)The aim of the study was to evaluate whether high-fructose corn syrup (HFCS) intake (20% beverages) impacts antioxidative structures and inflammation in the gingival tissue and masseter muscle of rats. Kefir was tested for ... -
Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against ehrlich ascites carcinoma-bearing balb/c mice
Bozkurt, Erhan; Atay, Emre; Pektaş, Gökhan; Ertekin, Ayşe; Vurmaz, Ayhan; Korkmaz, Ömer Adil; Sadi, Gökhan; Aslan, Esra; Koca, Oğuz Han; Pektaş, Mehmet Bilgehan (Iranian Journal of Pharmaceutical Research, 2020)We investigated the potential influence of kefir-induced juglone and resveratrol fractions (JRK) against Ehrlich Ascites Carcinoma (EAC) bearing BALB/c male mice. Kefir yeast was grown in the cell culture supplemented with ...
