Yazar "Söylemez, Zafer" için listeleme
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COMPARISON OF THE EFFECTS OF DOCETAXEL and AMYGDALIN TREATMENT ON CELL DEATH, INTEGRIN-? and INTEGRIN-? EXPRESSIONS IN DU145 PROSTATE CANCER CELL LINE
OBJECTIVE: Prostate cancer (PC) ranks second among cancer-related deaths in men, and most deaths are caused by metastasis. Integrins, which are cell surface receptors, play an important role in cancer metastasis. It has ... -
Determination of PDK1, SLC2A1, EGFR, PTEN, CD276 gene expression levels and IDH1 gene R132H polymorphism in brain tumor tissues
Korkmaz, Serhat; Arıkan Söylemez, Evrim Suna; Söylemez, Zafer; Solak, Mustafa (Turkey : Turkish Neurosurgi[c]al Society, 2023)Aim: This study aimed to determine IDH1 R132H codon and the mRNA levels of PDK1, SLC2A1, EGFR, PTEN, and CD276 genes in brain tumors. Material and methods: This study included 15 brain tumor tissues [pituitary adenoma ... -
Evaluation of IKK-?, NF-k?, p53, and Ki-67 Protein and Gene Expression in Neuroblastoma Cells Treated with Cisplatin
Elif, Kağa; Söylemez, Zafer; Kaga, Sadık (2024)Background: Neuroblastomas are extracranial solid tumors caused by the differentiation and uncontrolled proliferation of immature sympathetic nervous system cells. This study investigated the effects of the anticarcinogenic ... -
Farklı evre kolorektal tümörlerde bazı genlerin ifadelenme düzeylerinin araştırılması
Söylemez, Zafer (Afyonkarahisar Sağlık Bilimleri Üniversitesi Akademik Arşiv Sistemi, 2020)Kolorektal kanser dünyada en çok gözlenen kanserlerdendir. Dünya çapında tahmini 1.8 milyon yeni vaka ile önemli bir sağlık sorunudur. Kolorektal kanser, kolon, rektum ve/veya devamında kanserli büyümelerle tanımlanır. ... -
Investigation of the expression levels of CDH1, FHIT, PTEN, and TTPAL genes in colorectal tumors
Arıkan Söylemez, Evrim Suna; Söylemez, Zafer; Çilekar, Murat; Arıkan, Yüksel; Tokyol, Çiğdem; Kenger, İbrahim Halil; Solak, Mustafa (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL, 2022)Background/aim: The main aim of the study is to assess expression levels of CDH1, FHIT, PTEN, and TTPAL genes in tumors and peripheral bloods of colorectal cancer patients in staged I-IV. Materials and methods: Gene ... -
Investigation of the expression levels of CPEB4, APC, TRIP13, EIF2S3, EIF4A1, IFNg,PIK3CA and CTNNB1 genes in different stage colorectal tumors
Söylemez, Zafer; Arıkan, Evrim Suna; Solak, Mustafa; Arıkan, Yüksel; Tokyol, Çiğdem; Şeker, Hüseyin (Turkiye Klinikleri, 2021)Background/aim: The aim of the study is to assess expression levels of CPEB4, APC, TRIP13, EIF2S3, EIF4A1, IFNg, PIK3CA and CTNNB1 genes in tumors and peripheral bloods of colorectal cancer patients in stages I-IV. Materials ... -
Synergistic antiproliferative effects of the cisplatin and nimotuzumab combination through modulation of EGFR/MEK/ERK signaling in neuroblastoma
Korkmaz, Serhat; Elif, Kağa; Kaga, Sadık; Söylemez, Zafer; Erguner, Gizem Fatma; Söylemez, Evrım Suna Arıkan (2025)This study investigated the synergistic cytotoxic effect of cisplatin and nimotuzumab combination in neuroblastoma cells and their impact on EGFR/MEK/ERK signaling. Human neuroblastoma cells (SH-SY5Y) were treated with ...
