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COMPARISON OF THE EFFECTS OF DOCETAXEL and AMYGDALIN TREATMENT ON CELL DEATH, INTEGRIN-? and INTEGRIN-? EXPRESSIONS IN DU145 PROSTATE CANCER CELL LINE

Karaca, Çiğdem; Söylemez, Evrım Suna Arıkan; Aslan, Esra; Fırat, Fatma; Söylemez, Zafer (2024)

OBJECTIVE: Prostate cancer (PC) ranks second among cancer-related deaths in men, and most deaths are caused by metastasis. Integrins, which are cell surface receptors, play an important role in cancer metastasis. It has ...
Synergistic antiproliferative effects of the cisplatin and nimotuzumab combination through modulation of EGFR/MEK/ERK signaling in neuroblastoma

Korkmaz, Serhat; Elif, Kağa; Kaga, Sadık; Söylemez, Zafer; Erguner, Gizem Fatma; Söylemez, Evrım Suna Arıkan (2025)

This study investigated the synergistic cytotoxic effect of cisplatin and nimotuzumab combination in neuroblastoma cells and their impact on EGFR/MEK/ERK signaling. Human neuroblastoma cells (SH-SY5Y) were treated with ...