Yazar "Pektaş, Mehmet Bilgehan" için listeleme
-
Better neuroprotective profile of caffeic acid phenyl ester over resveratrol in non-traumatic ischemia-reperfusion injury of the spinal cord
Aslan, Esra; Boyacı, Mehmet Gazi; Güzel, Hilal; Pektaş, Mehmet Bilgehan (Taylor & Francis Group, 09.12.2021)Background Spinal cord ischemia has serious sequelae. The aim of this study is to investigate the effects of resveratrol and caffeic acid phenyl ester (CAPE), a propolis derivative, on spinal cord injury induced by ... -
Differential expression and in silico functional analysis of plasma microRNAs in the pathogenesis of non-segmental vitiligo
Pektaş, Suzan Demir; Kara, Murat; Doğan, Gürsoy; Pektaş, Mehmet Bilgehan; Baloğlu, Mehmet Cengiz; Sadi, Gökhan (Medknow Publications, 2022)Vitiligo is a disease characterized by acquired depigmentation, white macules, and patches on the skin due to the dysfunction of epidermal melanocytes. In this study, we attempt to profile the microRNA (miRNA) expression ... -
Echocardiographic and Laboratory Findings of Turkish Children during the First Attack of Acute Rheumatic Fever
Objective: In this study, we aim to determine demographic features and laboratory data of Turkish children who are diagnosed with acute rheumatic carditis and to evaluate echocardiographic indices of the left ventricle ... -
Effects of Lactobacillus Plantarum and Lactobacillus Helveticus on Renal Insulin Signaling, Inflammatory Markers, and Glucose Transporters in High-Fructose-Fed Rats
Korkmaz, Ömer Adil; Şumlu, Esra; Koca, Halit Buğra; Pektaş, Mehmet Bilgehan; Kocabaş, Aytaç; Sadi, Gökhan; Akar, Fatma (Mdpi, 2019)Background and Objectives: The excess consumption of fructose in the diet may cause metabolic syndrome, which is associated with an increased risk of kidney disease. There is limited data on probiotic treatment in ... -
Effects of Panax ginseng on cisplatin-induced testicular damage of rats
Aslan, Esra; Kumalar, Kübra; Güzel, Hilal; Demirel, Hasan Hüseyin; Çelik, Sefa; Pektaş, Mehmet Bilgehan (Abdullah KAYA, 2021)Abstract: Infertility has become an increasingly important health problem due to genetic, familial, hormonal, and congenital abnormalities, environmental and chemical reasons. This study aimed to investigate the effects ... -
How are cardiac functions altered in pediatric patients receiving oral iron supplementation due to anemia?
Hiçyılmaz, Merve; Pektaş, Ayhan; Gürel, Selçuk; Pektaş, Mehmet Bilgehan (Holistence Publications, 2021)Objective: This study aims to investigate whether oral iron supplementation improves structural and functional alterations by evaluating the echocardiography and electrocardiography findings of the pediatric patients with ... -
How Do Different Types of Physical Activity Affect Cardiac Functions in Children?
Pektaş, Ayhan; Pektaş, Mehmet Bilgehan (Marmara Üniversitesi, 2021)Background: This study aims to investigate how different types of regular physical activity affect cardiac functions in school children. Methods: This is a cross-sectional review of 15 children who are not engaged with any ... -
The inverse association between ANGPTL8 and PI3K-mTOR-PPAR gamma expressions in adipose tissue of high-fructose-fed rats: The modulatory effect of kefir
Akar, Fatma; Ceren, Güney; Özer, Hamdi Barbaros; Pektaş, Mehmet Bilgehan; Koca, Halit Buğra; Kocabaş, Aytaç; Sadi, Gökhan (İstanbul Üniversitesi, 2021)Background and Aims: The dietary high-fructose intake might be a risk factor for several metabolic diseases. Kefir, a fer mented milk product, has been proposed to have beneficial health effects. In this study, we aimed ... -
Kefir alters craniomandibular bone development in rats fed excess dose of high fructose corn syrup
Ekici, Ömer; Aslan, Esra; Güzel, Hilal; Korkmaz, Ömer Adil; Sadi, Gökhan; Gürol, Ahmet Muhtar; Boyacı, Mehmet Gazi; Pektaş, Mehmet Bilgehan (Springer, 06.10.2021)Introduction: Dietary high fructose corn syrup (HFCS) is involved in the pathogenesis of oral diseases as well as metabolic diseases. The aim of this study was to investigate the effects of HFCS-feeding on the craniomandibular ... -
Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity
Pektaş, Mehmet Bilgehan; Aslan, Esra; Güzel, Hilal; Korkmaz, Ömer Adil; Çeleğen, Kübra; Pektaş, Ayhan; Bostancı, Aykut; Sadi, Gökhan (De Gruyter, 03.05.2022)Objectives Phosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship ... -
Lactobacillus helveticus and Lactobacillus plantarum modulate renal antioxidant status in a rat model of fructose-induced metabolic syndrome
Korkmaz, Ömer Adil; Sadi, Gökhan; Kocabaş, Aytaç; Yıldırım, Onur Gökhan; Şumlu, Esra; Koca, Halit Buğra; Nalbantoğlu, Barbaros; Pektaş, Mehmet Bilgehan; Akar, Fatma (Inst Bioloska Istrazivanja Sinisa Stankovic, 2019)High dietary fructose intake causes a metabolic disorder and augments the risk of chronic kidney disease most likely due to oxidative stress. Probiotics could have antioxidant, antiinflammatory and immunoregulatory properties. ... -
Masseter muscle and gingival tissue inflammatory response following treatment with high-fructose corn syrup in rats: Anti-inflammatory and antioxidant effects of kefir
Ekici, Ömer; Aslan, Esra; Aladağ, Tuğçe; Güzel, Hilal; Korkmaz, Ömer Adil; Bostancı, Aykut; Sadi, Gökhan; Pektaş, Mehmet Bilgehan (Wiley, 2021)The aim of the study was to evaluate whether high-fructose corn syrup (HFCS) intake (20% beverages) impacts antioxidative structures and inflammation in the gingival tissue and masseter muscle of rats. Kefir was tested for ... -
Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against ehrlich ascites carcinoma-bearing balb/c mice
Bozkurt, Erhan; Atay, Emre; Pektaş, Gökhan; Ertekin, Ayşe; Vurmaz, Ayhan; Korkmaz, Ömer Adil; Sadi, Gökhan; Aslan, Esra; Koca, Oğuz Han; Pektaş, Mehmet Bilgehan (Iranian Journal of Pharmaceutical Research, 2020)We investigated the potential influence of kefir-induced juglone and resveratrol fractions (JRK) against Ehrlich Ascites Carcinoma (EAC) bearing BALB/c male mice. Kefir yeast was grown in the cell culture supplemented with ... -
Potential cytotoxic effects of borax alone and in combination with irinotecan on YKG1 glioblastoma cell-line
Yüksel, Yasemin; Çelik, Sefa; Aslan, Esra; Tosun, Murat; Uysal, Mükramin; Pektaş, Mehmet Bilgehan (Effect Publishing Agency ( EPA ), 2023)Glioblastoma Multiforme (GBM), which is a common and primary brain tumor in adults, is an important cause of death worldwide as an aggressive and treatment- resistant cancer tumor. In this cell culture study, the apoptotic ... -
Protective effects of resveratrol on permethrin-induced fetotoxicity in rats
Yüksel, Yasemin; Aslan, Esra; Tosun, Murat; Altunbaş, Korhan; Özden Akkaya, Özlem; Demirel, Hasan Hüseyin; Pektaş.Mehmet Bilgehan (Abdullah KAYA, 2023)Synthetic pyrethroid insecticides have been widely used for years to prevent harmful effects of insects and control disease vectors. In this study, the effects of resveratrol against the potential toxicity of permethrin, ...
