Yazar "Karaosmanoğlu, Cem" için listeleme
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CUL4B geninin yaşa bağlı katarakt ile ilişkisinin incelenmesi
Karaosmanoğlu, Cem (Afyonkarahisar Sağlık Bilimleri Üniversitesi, 2021)Yaşa Bağlı Katarakt, yaşlı nüfus arasında görüş kaybı ve bozukluğunun en yaygın nedeni olarak bilinmektedir. Lens epitel hücrelerinin apoptoza uğraması hücresel bazda kataraktın oluşumu için temel bir olaydır. CUL4B, ... -
IMPACT OF BLOOD PARAMETERS ON BCR/ABL1 P210 TESTING IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA: A PILOT STUDY
Karaosmanoğlu, Cem; Yıldız, Salıha Handan; Erdoğan, Müjgan Özdemir; Yavaşoğlu, Filiz; Doğuş, Haktan (2023)Objective: Chronic myeloid leukemia (CML) is one of the most common hematological malignancies derived from the BCR/ABL1 fusion gene. Patients with CML generally manifest leukocytosis with basophilia and neutrophilia. The ... -
Methylation analysis of histone 4-related gene HIST1H4F and its effect on gene expression in bladder cancer
Varol, Nuray; Keleş, İbrahim; Yıldız, Handan; Karaosmanoğlu, Cem; Karalar, Mustafa; Zengin, Kürşad; Sarıcı, Hasmet; Tokyol, Çiğdem (Elsevier/North-Holland, 2023)Recently, aberrant DNA methylation of the HIST1H4F gene (encodes Histone 4 protein) has been shown in many types of cancer, which may serve as a promising biomarker for early cancer diagnosis. However, the correlation ... -
Relationship between SIRT1 gene expression level and disease in age-related cataract cases
Ağaoğlu, Nihat Buğra; Varol, Nuray; Yıldız, Saliha Handan; Karaosmanoğlu, Cem; Duman, Rahmi; Özdemir Erdoğan, Müjgan; Solak, Mustafa (2019)Background/aim: Age-related cataract is the most important visual impairment all over the world. Epigenetic modifications, especially overexpression of histone deacetylases, have become the focus of interest for cataract ...
