Yazar "Aslan, Esra" için listeleme
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Better neuroprotective profile of caffeic acid phenyl ester over resveratrol in non-traumatic ischemia-reperfusion injury of the spinal cord
Aslan, Esra; Boyacı, Mehmet Gazi; Güzel, Hilal; Pektaş, Mehmet Bilgehan (Taylor & Francis Group, 09.12.2021)Background Spinal cord ischemia has serious sequelae. The aim of this study is to investigate the effects of resveratrol and caffeic acid phenyl ester (CAPE), a propolis derivative, on spinal cord injury induced by ... -
Cisplatin ile testis hasarı oluşturulan yetişkin erkek sıçanlarda panax ginseng'in hücre ölümü üzerine etkisi
Kumalar, Kübra (Afyonkarahisar Sağlık Bilimleri Üniversitesi Akademik Arşiv Sistemi, 2019)ÖZET Cisplatin ile Testis Hasarı Oluşturulan Yetişkin Erkek Sıçanlarda Panax Ginseng'in Hücre Ölümü Üzerine Etkisi İnfertilite genetik, ailevi, hormonal nedenler, doğumsal anormallikler, çevresel ve kimyasal nedenlerle ... -
Detection of antitumoral effects of quercetin through protein synthesis associated with argyrophilic nucleolar-regulating region
Yılmaz, Seher; Aslan, Esra; Doğanyiğit, Züleyha (SAGE Publications Ltd, 2021)Quercetin is a natural flavonoid with potential anticancer properties without significant cytotoxicity in normal tissues. However, the effects of quercetin on Ehrlich ascites carcinoma (EAC) have not yet been clarified. ... -
Does the anticholinergic drug Biperiden affect early neural tube development in chick embryos?
Güzel, Hilal; Aslan, Esra (Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi Dekanlığı, 2022)Objective: Biperiden (BPD) is an anticholinergic agent that acts both centrally and peripherally. It is used to counteract both extrapyramidal side effects of neuroleptic treatment and symptoms of Parkinson’s disease in ... -
Does the anticholinergic drug Biperiden affect early neural tube development in chick embryos?
Güzel, Hilal; Aslan, Esra (Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi Dekanlığı, 2022)Objective: Biperiden (BPD) is an anticholinergic agent that acts both centrally and peripherally. It is used to counteract both extrapyramidal side effects of neuroleptic treatment and symptoms of Parkinson’s disease in ... -
Effect of buscopan, a compound that alleviates cramps, on the developing nervous system of the chick embryo
Ertekin, Ayşe; Atay, Emre; Bozkurt, Erhan; Aslan, Esra (Wiley, 29.05.2021)Background Buscopan is used to treat stomach cramps including those resulting from irritable bowel syndrome, bladder cramps, and pain related to menstruation. Its pregnancy category is determined as C. It has been shown ... -
Effects of 2-Aminoethyl Diphenylborinate, a Modulator of Transient Receptor Potential and Orai Channels in Subarachnoid Hemorrhage: An Experimental Study
Boyacı, Mehmet Gazi; Rakip, Usame; Aslan, Adem; Koca, Halit Buğra; Aslan, Esra; Korkmaz, Serhat; Yıldızhan, Serhat (Elsevier Science Inc, 2019)BACKGROUND: Cerebral vasospasm remains a serious problem affecting morbidity and mortality in patients with subarachnoid hemorrhage (SAH) during neurosurgery. We aimed to demonstrate the role of the transient receptor ... -
Effects of Panax ginseng on cisplatin-induced testicular damage of rats
Aslan, Esra; Kumalar, Kübra; Güzel, Hilal; Demirel, Hasan Hüseyin; Çelik, Sefa; Pektaş, Mehmet Bilgehan (Abdullah KAYA, 2021)Abstract: Infertility has become an increasingly important health problem due to genetic, familial, hormonal, and congenital abnormalities, environmental and chemical reasons. This study aimed to investigate the effects ... -
Effects of resveratrol and 1,3-bis(2-chloroethyl)-1-nitrosurea combination on YKG1 glioblastoma cells
Pektaş, Gökhan; Aslan, Esra; Güzel, Hilal; Demirciler Yavaş, Betül; Çelik, Sefa (Abdullah KAYA, 2021)Glioblastoma is a primary malignant brain tumor that can be treated with 1,3-bis(2-chloroethyl)-1-nitrosurea(BiCNU/carmustine). Resveratrol is a natural phenol that can interfere with apoptosis. This study aims to investigate ... -
Impact of Bisphenol A on neural tube development in 48-hr chicken embryos
Atay, Emre; Ertekin, Ayşe; Bozkurt, Erhan; Aslan, Esra (Wiley, 2020)Objectives Bisphenol A (BPA) is one of the most heavily produced chemicals in the world. BPA is involved in the production of many substances such as cosmetics, various foodstuffs, toys, personal care products, detergents ... -
In Vitro Investigation of the Effects of Cape Contribution to Chemotherapeutic Drug Treatment on the Neuroblastoma Cell Line (SH SY- 5Y) on the Inflammatory Process
Karaca, Çiğdem; Susam Şen, Hilal; Fırat, Fatma; Aslan, Esra (Gaziantep İslam Bilim ve Teknoloji Üniversitesi, 2022)Neuroblastoma is a sympathetic nervous system tumor with a 5-year survival rate of less than 50% in high-risk patients that are unresponsive to conventional multimodal treatments. Although chemotherapy, radiotherapy, and ... -
The investigation of the antitumoral effect of Cornus mas L in mice with ehrlich solid tumor
Yılmaz, Seher; Alpa, Şerife; Göçmen, Ayşe Yeşim; Ülger, Harun; Aslan, Esra; Yay, Arzu Hanım; Ertekin, Tolga; Nisari, Mehtap; Yalçın, Betül (Comenius University, 2020)AIM: Cornus mas L is commonly used due to its anti-inflammatory, anti-carcinogenic and anti-oxidant properties. In the study, the effects of C. mas L extract on a solid tumor were examined in the Ehrlich solid tumor model ... -
Investigation of the protective effect of vitamin K1 on the heart in streptozotocin induced type 1 diabetes model
Bilir, Abdülkadir; Aslan, Esra (Holistence Publications, 2022)Maternal and fetal diabetes are directly associated with increased morbidity and mortality risk. Along with this increased risk, the incidence of congenital malformations in newborns also increases depending on the mother’s ... -
Kefir alters craniomandibular bone development in rats fed excess dose of high fructose corn syrup
Ekici, Ömer; Aslan, Esra; Güzel, Hilal; Korkmaz, Ömer Adil; Sadi, Gökhan; Gürol, Ahmet Muhtar; Boyacı, Mehmet Gazi; Pektaş, Mehmet Bilgehan (Springer, 06.10.2021)Introduction: Dietary high fructose corn syrup (HFCS) is involved in the pathogenesis of oral diseases as well as metabolic diseases. The aim of this study was to investigate the effects of HFCS-feeding on the craniomandibular ... -
Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity
Pektaş, Mehmet Bilgehan; Aslan, Esra; Güzel, Hilal; Korkmaz, Ömer Adil; Çeleğen, Kübra; Pektaş, Ayhan; Bostancı, Aykut; Sadi, Gökhan (De Gruyter, 03.05.2022)Objectives Phosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship ... -
Masseter muscle and gingival tissue inflammatory response following treatment with high-fructose corn syrup in rats: Anti-inflammatory and antioxidant effects of kefir
Ekici, Ömer; Aslan, Esra; Aladağ, Tuğçe; Güzel, Hilal; Korkmaz, Ömer Adil; Bostancı, Aykut; Sadi, Gökhan; Pektaş, Mehmet Bilgehan (Wiley, 2021)The aim of the study was to evaluate whether high-fructose corn syrup (HFCS) intake (20% beverages) impacts antioxidative structures and inflammation in the gingival tissue and masseter muscle of rats. Kefir was tested for ... -
Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against ehrlich ascites carcinoma-bearing balb/c mice
Bozkurt, Erhan; Atay, Emre; Pektaş, Gökhan; Ertekin, Ayşe; Vurmaz, Ayhan; Korkmaz, Ömer Adil; Sadi, Gökhan; Aslan, Esra; Koca, Oğuz Han; Pektaş, Mehmet Bilgehan (Iranian Journal of Pharmaceutical Research, 2020)We investigated the potential influence of kefir-induced juglone and resveratrol fractions (JRK) against Ehrlich Ascites Carcinoma (EAC) bearing BALB/c male mice. Kefir yeast was grown in the cell culture supplemented with ... -
Potential cytotoxic effects of borax alone and in combination with irinotecan on YKG1 glioblastoma cell-line
Yüksel, Yasemin; Çelik, Sefa; Aslan, Esra; Tosun, Murat; Uysal, Mükramin; Pektaş, Mehmet Bilgehan (Effect Publishing Agency ( EPA ), 2023)Glioblastoma Multiforme (GBM), which is a common and primary brain tumor in adults, is an important cause of death worldwide as an aggressive and treatment- resistant cancer tumor. In this cell culture study, the apoptotic ... -
The protective effect of apelin-13 on cardiorenal toxicity induced by cyclophosphamide
Kutlay, Özden; Keskin Aktan, Arzu; Aslan, Esra (Canadian Science Publishing, 19.10.2021)Cyclophosphamide is a chemotherapeutic drug that is widely used in the clinic and can cause multi-organ toxicity. Apelin-13 is an endogenous adipocytokine with antioxidant properties. Therefore, this study investigated the ... -
Protective effect of valproic acid on ischemia-reperfusion induced spinal cord injury in a rat model
Akpınar Oruç, Oya; Boyaci, Mehmet Gazi; Ozdinç, Şerife; Celik, Sefa; Aslan, Esra (Abingdon : Taylor & Francis, 2023)Purpose: This study aims to determine the anti-inflammatory, antioxidant, and anti-apoptotic effects of valproic acid (VPA) on rat spinal cord tissue in ischemia-reperfusion (IR) injury model created by abdominal aorta ...