Yazar "Akarca-Dizakar, Saadet Ozen" için listeleme
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AGK2, a SIRT2 inhibitor, ameliorates D-galactose-induced liver fibrosis by inhibiting fibrogenic factors
Bahar, Asli Nur; Keskin-Aktan, Arzu; Akarca-Dizakar, Saadet Ozen; Sonugur, Gizem; Akbulut, Kazime Gonca (Wiley, 2024)In our study, we aimed to investigate the effect of SIRT2 inhibition on function, fibrosis and inflammation in liver fibrosis induced by D-Galactose (D-Gal) administration. A total of 32 3-month-old Sprague Dawley rats ... -
Protective Effect of Pharmacological SIRT2 Inhibition on Renal Dysfunction, Fibrosis, TGF-?1/?-Catenin, and Klotho Signaling in D-Galactose-Induced Aging Model
Keskin-Aktan, Arzu; Bahar, Asli Nur; Sonugur, Fatma Gizem; Akarca-Dizakar, Saadet Ozen; Akbulut, Kazime Gonca (Asia Pacific Acad Science Pte. Ltd., 2023)Background: Fibrosis induced by transforming growth factor -01 (TGF-01) activity and the Wnt/0-catenin pathway is a significant hallmark of progressive kidney disease and kidney aging. We aimed to investigate the effects ...
