Yazar "Şıhoğlu Tepe, Arzuhan" için listeleme
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Determination of the interaction between the receptor binding domain of 2019-nCoV spike protein, TMPRSS2, cathepsin B and cathepsin L, and glycosidic and aglycon forms of some flavonols
İstifli, Erman Salih; Şıhoğlu Tepe, Arzuhan; Netz, Paulo A.; Sarıkürkçü, Cengiz; Kılıç, İbrahim Halil; Tepe, Bektaş (Scientific and Technical Research Council of Turkey, 30.08.2021)The novel coronavirus (COVID-19, SARS-CoV-2) is a rapidly spreading disease with a high mortality. In this research, the interactions between specific flavonols and the 2019-nCoV receptor binding domain (RBD), transmembrane ... -
Draba cemileae (Karaer): Phytochemical composition, antioxidant and enzyme inhibitory activity
Cüce, Mustafa; Demir, Ersin; Şıhoğlu Tepe, Arzuhan; Sarıkürkçü, Cengiz (Elsevier, 2022)Plant polyphenols have always attracted the attention of researchers with their excellent biological activity potentials. In this study, roots, leaves and seeds of Draba cemileae (Karaer) were evaluated for their chemical ... -
In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel coronavirus and cellular proteases and their pharmacokinetic properties
İstifli, Erman Salih; Netz, Paulo A.; Şıhoğlu Tepe, Arzuhan; Hüsunet, Mehmet Tahir; Sarıkürkçü, Cengiz; Tepe, Bektaş (Taylor & Francis Inc, 2020)Coronavirus Disease 2019 (COVID-19) has infected more than thirty five million people worldwide and caused nearly 1 million deaths as of October 2020. The microorganism causing COVID-19 was named as Severe Acute Respiratory ... -
Interaction of certain monoterpenoid hydrocarbons with the receptor binding domain of 2019 novel coronavirus (2019-nCoV), transmembrane serine protease 2 (TMPRSS2), cathepsin B, and cathepsin L (CatB/L) and their pharmacokinetic properties
İstifli, Erman Salih; Şıhoğlu Tepe, Arzuhan; Sarıkürkçü, Cengiz; Tepe, Bektaş (Tubitak Scientific & Technical Research Council Turkey, 2020)As of June 2020, the coronavirus disease 19 (COVID-19) caused by the 2019 new type coronavirus (2019-nCoV) infected more than 7,000,000 people worldwide and caused the death of more than 400,000 people. The aim of this ... -
Molecular interactions of some phenolics with 2019-nCoV and related pathway elements
İstifli, Erman Salih; Şıhoğlu Tepe, Arzuhan; Sarıkürkçü, Cengiz; Tepe, Bektaş (Pamukkale University, 2021)As of June 2021, the novel coronavirus disease (SARS-CoV-2) resulted in 180 million cases worldwide and resulted in the death of approximately 4 million people. However, an effective pharmaceutical with low side effects ... -
Nutraceutical extracts from some endemic Onosma (O. circinnata, O. bornmuelleri, and O. angustissima) species: LC–ESI-MS/MS–based polyphenol profile, antioxidant and enzyme inhibition activities
Sarıkürkçü, Cengiz; Şahinler, Saliha Şeyma; Özer, Mehmet Sabih; Şıhoğlu Tepe, Arzuhan (Wiley, 18.06.2021)This study aimed to determine the chemical composition of methanol extracts from Onosma circinnata, Onosma bornmuelleri, and Onosma angustissima and to investigate their antioxidant and enzyme inhibitory activities. ... -
Phytochemical Analysis and Biological Evaluation of Two Endemic Onosma Species (Onosma cappadocica and O. rutilum)
Kırkan, Bülent; Sarıkürkçü, Cengiz; Şıhoğlu Tepe, Arzuhan (AMG Transcend Association, 12.02.2022)Onosma species have been used by the public for centuries to treat various diseases. This study aimed to analyze the chemical composition, antioxidant, and enzyme inhibitory activity potentials of the methanol extracts of ... -
Understanding the molecular interaction of SARS-CoV-2 spike mutants with ACE2 (angiotensin converting enzyme 2)
İstifli, Erman Salih; Netz, Paulo A.; Şıhoğlu Tepe, Arzuhan; Sarıkürkçü, Cengiz; Tepe, Bektaş (Taylor & Francis Group, 08.09.2021)Covid-19 is a viral disease caused by the virus SARS-CoV-2 that spread worldwide and caused more than 4.3 million deaths. Moreover, SARS-CoV-2 still continues to evolve, and specifically the E484K, N501Y, and South Africa ... -
Wild mushrooms from Ilgaz Mountain National Park (Western Black Sea, Turkey): element concentrations and their health risk assessment
Keskin, Feyyaz; Sarıkürkçü, Cengiz; Demirak, Ahmet; Akata, Ilgaz; Şıhoğlu Tepe, Arzuhan (Springer, 11.01.2022)The purpose of this study was to determine Fe, Cd, Cr, Se, P, Cu, Mn, Zn, Al, Ca, Mg, and K contents of some edible (Chlorophyllum rhacodes, Clavariadelphus truncatus, Clitocybe nebularis, Hydnum repandum, Hygrophorus ...
