Yazar "Çelik, Sefa" için listeleme
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Berberine synergizes with cisplatin via Inducing apoptosis on A549 non-small cell lung cancer cells
Becit Kızılkaya, Merve; Öncü, Şeyma; Şen, Serkan; Çelik, Sefa (Fatma Taşçı, 2023)Objective: Lung cancer is the most common cause of morbidity and mortality. Platinum-based chemotherapy, which is the primary line of treatment, offers limited benefit due to drug resistance and side effects. Berberine ... -
Changes in genotoxicity, inflammatory and oxidative stress parameters of workers in marble processing plants
Becit, Merve; Çilekar, Şule; Başaran, Mustafa Mert; Koca, Halit Buğra; Çelik, Sefa; Aydın Dilsiz, Sevtap (Academic Press Inc., 2021)Workers in marble processing plants are at high risk of exposure to high levels of marble dust containing silica, but there are limited studies evaluating the genotoxicity and oxidative stress parameters of workers ... -
The Effect of Nasal Steroid and Antihistamine Use on Total Oxidative Stress and Antioxidant Status in the Treatment of Allergic Rhinitis
Kahveci, Orhan Kemal; Kuzu, Selçuk; Altıntaş, Mustafa; Vurmaz, Ayhan; Çelik, Sefa (SAGE Publications Inc., 2021)Introduction: The purpose of this study is to determine the post-treatment levels of total oxidant status (TOS) and total antioxidant status (TAS), that are increased due to pathophysiology, and to compare those with ... -
Effects of Panax ginseng on cisplatin-induced testicular damage of rats
Aslan, Esra; Kumalar, Kübra; Güzel, Hilal; Demirel, Hasan Hüseyin; Çelik, Sefa; Pektaş, Mehmet Bilgehan (Abdullah KAYA, 2021)Abstract: Infertility has become an increasingly important health problem due to genetic, familial, hormonal, and congenital abnormalities, environmental and chemical reasons. This study aimed to investigate the effects ... -
Effects of resveratrol and 1,3-bis(2-chloroethyl)-1-nitrosurea combination on YKG1 glioblastoma cells
Pektaş, Gökhan; Aslan, Esra; Güzel, Hilal; Demirciler Yavaş, Betül; Çelik, Sefa (Abdullah KAYA, 2021)Glioblastoma is a primary malignant brain tumor that can be treated with 1,3-bis(2-chloroethyl)-1-nitrosurea(BiCNU/carmustine). Resveratrol is a natural phenol that can interfere with apoptosis. This study aims to investigate ... -
Effects of three endotracheal tube cuff pressure control measures on microaspiration of gastric content: Study protocol for randomised controlled trial
Soyer Er, Özlem; Yavuz van Giersbergen, Meryem; Çelik, Sefa (Wiley, 24.08.2022)Aim To analyse the effect of endotracheal tube cuff pressure control measures on the microaspiration of the stomach contents by measuring at the level of pepsin in deep tracheal aspiration. Design A single-blind, ... -
Evaluation of effectiveness of the containing energized oxygen molecules herbal product on the wound healing
Okumuş, Nurullah; Erdoğmuş, Sevim Feyza; Erdal Altıntaş, Özlem; Demirel, Hasan Hüseyin; Çelik, Sefa (Afyon Kocatepe Üniv. Veteriner Fak., 2023)In recent years, the interest in herbal medicinal products has been increasing with the development of advanced formulation technologies related to the use of the medicinal and aromatic plants. These developed products are ... -
Potential cytotoxic effects of borax alone and in combination with irinotecan on YKG1 glioblastoma cell-line
Yüksel, Yasemin; Çelik, Sefa; Aslan, Esra; Tosun, Murat; Uysal, Mükramin; Pektaş, Mehmet Bilgehan (Effect Publishing Agency ( EPA ), 2023)Glioblastoma Multiforme (GBM), which is a common and primary brain tumor in adults, is an important cause of death worldwide as an aggressive and treatment- resistant cancer tumor. In this cell culture study, the apoptotic ... -
Priapism and its surgical treatment in a cat
Sarıtaş, Zülfükar Kadir; Korkmaz, Musa; Görücü, Fatma; Çelik, Sefa (Ankara Univ Press, 2021)This study details a case of priapism in a 3-year-old, male, crossbreed cat weighing 5,4 kg treated successfully with surgery. The cat was brought to the Afyon Kocatepe University Veterinary Health Application and Research ... -
Production of fungal chitosan and fabrication of fungal chitosan/polycaprolactone electrospun nanofibers for tissue engineering
Erdoğmuş, Sevim Feyza; Erdal Altıntaş, Özlem; Çelik, Sefa (Wiley-Liss, 2023)The present study investigated that chitosan production of Rhizopus oryzae NRRL 1526 and Aspergillus niger ATCC 16404. Fungal chitosans were characterized by scanning electron microscopy (SEM)-energy dispersive X-ray ... -
Protective effect of valproic acid on ischemia-reperfusion induced spinal cord injury in a rat model
Akpınar Oruç, Oya; Boyaci, Mehmet Gazi; Ozdinç, Şerife; Celik, Sefa; Aslan, Esra (Abingdon : Taylor & Francis, 2023)Purpose: This study aims to determine the anti-inflammatory, antioxidant, and anti-apoptotic effects of valproic acid (VPA) on rat spinal cord tissue in ischemia-reperfusion (IR) injury model created by abdominal aorta ... -
The relationship of biochemical factors related to calcium metabolism with temporomandibular disorders
Ekici, Ömer; Çelik, Sefa (Elsevier, 21.10.2022)Objective: The aim of this study is to investigate the relationship between calcium metabolism-related biochemical factors (alkaline phosphatase, vitamin D, parathyroid hormone (PTH), calcium, phosphorus and magnesium), ... -
The Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure
Dural, İbrahim Etem; Onrat, Ersel; Çelik, Sefa; Vurmaz, Ayhan; Yalım, Zafer; Gökaslan, Serkan; Gökaslan, Çiğdem; Korucu, Cem; Aksu, Uğur (AVES Yayıncılık, 2022)Objective: Dietary recommendations, in addition to medications, have recently become important in the treatment of heart failure. Our study aimed to show the positive effects of both milk chocolate and dark chocolate on ... -
Role of aortic stiffness and inflammation in the etiology of young-onset hypertension
Background/aim: Young-onset hypertension is a form of condition diagnosed in patients aged below 40. Cytokines such as interleukin (IL)-6 and also MCP-1 may play a role in the development of arterial hypertension. Aortic ... -
The role of endothelial dysfunction and inflammation in young-onset hypertension
Gökaslan, Serkan; Özer Gökaslan, Çiğdem; Çelik, Sefa (Pagepress Publ, 2020)Young-onset hypertension is defined as hypertension seen in patients under 40 years of age. The relationship between hypertension and inflammation has been identified. In hypertensive patients, YKL-40 has been shown to be ...
