Peri-and post-operative comparison of 24 hour ph monitoring results in patients who with laparoscopic ant-reflux surgery

Abstract

ntroduction: Gastroesophageal reflux disease (GERD) is a common medical problem affecting the quality of life and causing morbidity. Twenty four hour pH monitoring is the most sensitive and specific test in diagnos- ing GERD. The aim of this study is to compare pre- and post-operative 24 h pH monitoring results, life quality, and demographic features of patients with GERD diagnosis who underwent laparoscopic ant-reflux surgery. Materials and Methods: In this study, 40 patients who were referred to Afyon Kocatepe university hospital general surgery clinic between January 2016 and August 2017, diagnosed with GERD and underwent laparo- scopic ant-reflux surgery were enrolled. The results of pre- and at least 3 months post-operative 24-h pH monitoring were compared. Results: Of those 40 patients who were enrolled to the study 16(40%) were male and 24 (60%) were female. The overage age of the male patients was 47.65±15.3, and the average age of the females was 42.55±13.5. It was observed that the quality of life scores of the patients, evaluated with GERD-HRQL in the pre-oper- ative period, decreased statistically significantly in the post-operative period. (p=0.001) The pre-operative DeMeester Score of all patients was above the normal value, and when the post-operative analysis results were examined, it was observed that the reflux parameter results decreased. Conclusion: It has been shown that the post-operative 24-h pH monitoring results in patients who underwent laparoscopic anti-reflux surgery decreased significantly compared to the pre-operative results. It was observed that the symptoms were brought under control and the quality of life was improved in the patients. Based on these results, Nissen fundoplication is a successful and effective procedure. 24 h pH monitoring should be done post anti-reflux surgery to assess the effectiveness of the procedure and symptom post-surgery.