Advanced Search

Show simple item record

dc.contributor.authorBilir, Filiz
dc.contributor.authorChkhikvadze, Mariam
dc.contributor.authorYalçınkaya Yılmaz, Ayşe
dc.contributor.authorKöse, Osman
dc.contributor.authorArıöz, Dağıstan Tolga
dc.identifier.citationBilir, F., Chkhikvadze, M., Yilmaz, A. Y., Kose, O., & Arıöz, D. T. (2022). Prognostic value of systemic inflammation response index in patients with persistent human papilloma virus infection. Ginekologia Polska.en_US
dc.description.abstractObjectives: Persistent human papilloma virus (HPV) infection is a risk factor for the progression of cervical neoplasia into invasive carcinoma. Many inflammatory markers obtaining from hemogram parameters as platelets, monocytes, lymphocytes, and neutrophils or their ratios are still under investigation in recent decades, especially in the oncology era. Indeed, there have not been enough data about the relationship between these parameters and cervical cancer in the literature. Our primary aim was to investigate the possible relationship between the persistent HPV, which is one of the significant risk factors of cervical cancer, and these inflammatory markers. Further, we can add an easy follow-up parameter in women with persistent HPV infection. Material and methods: The study included patients between 30–65 years old, tested positive for HPV, and afterward had an HPV control test between January 2015 and June 2020. Results: The study included 114 HPV DNA-positive patients. The mean age was 43 (standard deviation 8.7), and 41 of them (36%) had persistent HPV, but the remaining 73 (64%) did not. The baseline neutrophil/lymphocyte ratio (NLR) value was 2.1, platelet/lymphocyte ratio (PLR) was 133, monocyte/lymphocyte ratio (MLR) was 0.28, and systemic inflammation response index (SIRI) was 0.9. All the parameters were significantly higher in the persistent HPV group compared to the non-persistent group. Patients who had 0.65 and under this had a significantly lower risk of persistent HPV. Conclusions: Persistent HPV disease can be predicted with an elevated SIRI, NLR, and other hematologic parameters. So, we can closely follow up with these patients with different algorithms to prevent cervical cancer.en_US
dc.publisherVia Medicaen_US
dc.subjectSystemic inflammation response indexen_US
dc.subjectNeutrophil to lymphocyte ratioen_US
dc.subjectPlatelet to lymphocyte ratioen_US
dc.subjectPersistent HPVen_US
dc.titlePrognostic value of systemic inflammation response index in patients with persistent human papilloma virus infectionen_US
dc.departmentAFSÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.contributor.institutionauthorBilir, Filiz
dc.contributor.institutionauthorChkhikvadze, Mariam
dc.contributor.institutionauthorYalçınkaya Yılmaz, Ayşe
dc.contributor.institutionauthorArıöz, Dağıstan Tolga
dc.relation.journalGinekologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

Files in this item


This item appears in the following Collection(s)

Show simple item record