Browsing PubMed İndeksli Yayınlar Koleksiyonu by Subject "Melatonin"

Now showing items 1-3 of 3

Antioxidant role of melatonin against nicotine's teratogenic effects on embryonic bone development

Yılmaz, Halil; Ertekin, Tolga; Atay, Emre; Nisari, Mehtap; Susar Güler, Hatice; Al, Özge; Payas, Ahmet; Yılmaz, Seher (Mashhad Univ Med Sciences, 2018)

Objective(s): This study investigated the possible effects of low (3 mg/kg) and high (6 mg/kg) doses of nicotine on the skeletal development of rat fetuses by the double staining method and the protective role of melatonin ...
Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region-associated protein synthesis and TLR4/NF-κB signaling pathway

Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna (Wiley-Blackwell, 2022)

In this study, the protective effect of melatonin was investigated in lipopolysaccharide induced sepsis model. Twenty-eight rats were randomly divided: Control, Melatonin, LPS and LPS + Melatonin. After LPS application, ...
SIRT2 and FOXO3a expressions in the cerebral cortex and hippocampus of young and aged male rats: antioxidant and anti-apoptotic effects of melatonin

Keskin Aktan, Arzu; Akbulut, Kazime Gonca; Abdi, Samira; Akbulut, Hakan (Akadémiai Kiadó, 27.10.2021)

Melatonin has antioxidant, anti-apoptotic and anti-aging efects in the brain. Sirtuin2 (SIRT2) accumulates in the central nervous system with aging, and its inhibition appears to be protective in aging and aging-related ...