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dc.contributor.authorDoğan, Mustafa
dc.contributor.authorAkdoğan, Müberra
dc.contributor.authorGülyeşil, Furkan Fatih
dc.contributor.authorSabaner, Mehmet Cem
dc.contributor.authorGobeka, Hamidu Hamisi
dc.date.accessioned2021-05-05T22:14:09Z
dc.date.available2021-05-05T22:14:09Z
dc.date.issued2020
dc.identifier.issn0816-4622
dc.identifier.issn1444-0938
dc.identifier.urihttps://doi.org/10.1111/cxo.13070
dc.identifier.urihttps://hdl.handle.net/20.500.12933/332
dc.descriptionakdogan, muberra/0000-0003-4846-312X; Sabaner, Mehmet Cem/0000-0002-0958-9961; Gobeka, Hamidu Hamisi/0000-0002-7656-3155; DOGAN, Mustafa/0000-0001-7237-9847en_US
dc.descriptionWOS:000525923100001en_US
dc.descriptionPubMed: 32285487en_US
dc.description.abstractBackground The purpose of this study was to report the effects of smoking on retinal vascular parameters. Methods In this cross-sectional study design, 24 smokers were included as a study group and 26 age- and sex-matched non-smokers as a control group. A detailed ophthalmic examination including review of medical history, visual acuity testing, intraocular pressure measurement by Goldmann applanation tonometry, ocular movement and pupillary reflex examination, slitlamp biomicroscopy as well as dilated funduscopic examination were undertaken in all participants. Participants underwent optical coherence tomography angiography (OCT-A) scanning with RTVue XR Avanti AngioVue OCT-A (Optovue, Fremont, CA, USA) as well as the measurement of axial length using an AL Scan (Nidek Co., Ltd., Gamagori, Japan). Results The study comprised of 18 men and six women with a mean age of 28.1 +/- 4.8 years in the study group and 19 men and seven women with a mean age of 27.4 +/- 2.7 years in the control group. The mean exposure to cigarette smoking was 3.3 +/- 1.0 pack-years. Total vascular density, parafoveal vascular density and perifoveal vascular density in the deep capillary plexus observed with OCT-A were significantly lower in the smoking group compared to the control group (p = 0.02, 0.01 and 0.01, respectively). Conclusion Retinal vascular changes caused by cigarette smoking may occur even at low pack-year exposure. These changes, which can be demonstrated by OCT-A, may reflect the early impact of cigarette smoking on the microvascular system.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcigarette smokingen_US
dc.subjectoptical coherence tomography angiographyen_US
dc.subjectvessel densityen_US
dc.titleCigarette smoking reduces deep retinal vascular densityen_US
dc.typearticleen_US
dc.departmentAFSÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.contributor.institutionauthorDoğan, Mustafa
dc.contributor.institutionauthorAkdoğan, Müberra
dc.contributor.institutionauthorGülyeşil, Furkan Fatih
dc.contributor.institutionauthorSabaner, Mehmet Cem
dc.identifier.doi10.1111/cxo.13070
dc.identifier.volume103en_US
dc.identifier.issue6en_US
dc.identifier.startpage838en_US
dc.identifier.endpage842en_US
dc.relation.journalClinical And Experimental Optometryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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