Heliotropium bacciferum essential oil extraction: Compositions determination by GC-MS and anti-inflammatory and antibacterial activities evaluation

Abstract

Heliotropium bacciferum plant is very important and has been used for medicinal values since ancient times. The present study deals with the extraction of essential oil (0.14 w/w) of this plant and its GC-MS analysis, antiinflammatory, and anti-bacterial activities evaluation. GC analysis of essential oil confirmed 76 compounds with 49 terpenes and oxygenated hydrocarbons. The main components of this essential oil are agarospirol (15.15 %), rosifoliol (9.41 %), elemol (8.96 %), tau.-cadinol (8.05 %), linalool (5.37 %), shyobunol (5.36 %) cyclohexylmethyl tridecyl ester of oxalic acid (4.74 %), respectively. The essential oil showed quite good antiinflammatory activity while this oil indicated excellent anti-bacterial activity against 3 g-positive pathogenic bacteria (Bacillus subtilusATCC 6633, Entrococcus faecalis ATCC 29212, and Bacillus cereusATCC 11778). The essential oil of Heliotropium bacciferum showed great potential as an anti-inflammatory and anti-bacterial agent. Therefore, the reported extraction and GC-MS analysis methods are useful to extract the essential oil and determine the composition of other plants. The extracted essential oil may be used to treat several diseases.