Advanced Search

Show simple item record

dc.contributor.authorApaydın, Mahmut
dc.contributor.authorDizen Kazan, Elif
dc.contributor.authorBeysel, Selvihan
dc.contributor.authorSarı, Alper
dc.contributor.authorÖzgül, Esra
dc.contributor.authorCengiz, Hasret
dc.contributor.authorDemirci, Taner
dc.contributor.authorYılmazer, Mehmet
dc.identifier.citationApaydin, M., Kazan, E. D., Beysel, S., Sari, A., Özgül, E., Cengiz, H., ... & Yilmazer, M. (2022). The novel predictor of metabolic risk in patients with polycystic ovary syndrome: could it be the visceral adiposity index?. European Review for Medical and Pharmacological Sciences, 26(19), 7182-7187.en_US
dc.description.abstractOBJECTIVE: Polycystic ovary syndrome (PCOS) is the most common endocrinological disorder in women of reproductive age, often accompanied by high androgen levels, irregular menstrual cycles and polycystic ovaries. In addition, patients with PCOS also present with an increase in abdominal adipose tissue and insulin resistance. Recently, the gender-specific mathematical formulation called visceral adiposity index (VAI) has been widely used in assessing cardiometabolic risk. This study aimed at comparing the VAI values of patients with PCOS, patients with idiopathic hirsutism (IH) and a control group. PATIENTS AND METHODS: We obtained demographic data, laboratory results and anthropometric measurements of patients from the hospital database. We retrospectively grouped all cases included in the study as PCOS (n = 52), IH (n = 57) and control (n = 58) according to the diagnoses. We also took venous samples for hormone and biochemical tests in the early follicular phase of the menstrual cycle, at least 8-10 hours after fasting in the early morning hours. Finally, we evaluated the variables using SPSS 22.0 software (IBM Corp., Armonk, NY, USA). RESULTS: We included 167 female individuals in the study. Of these, 57 (34.1%) were diagnosed with IH, while 52 (31.1%) were diagnosed with PCOS. The control group comprised 58 (34.8%) healthy female individuals. The median age of the study group was 25 years [interquartile range (IQR) = 8 years]. The age, height, weight, body mass index (BMI) and waist circumference values of the groups were similar. We found that the VAI values among the groups were significantly different (p = 0.028). Post-hoc analysis determined that this was due to the difference between the group with PCOS and the control group. In addition, we found significantly high HOMA-IR, fasting insulin and androgen levels in the group with PCOS (p < 0.001). CONCLUSIONS: After comparing data in groups with similar BMI levels, we found significantly high VAI values in patients with PCOS. The results reinforce the idea that VAI is a useful marker easily obtained in daily practice for assessing the cardiometabolic risk of patients with PCOS.en_US
dc.subjectCardiometabolic risken_US
dc.subjectInsulin resistanceen_US
dc.subjectPolycystic ovary syndromeen_US
dc.titleThe novel predictor of metabolic risk in patients with polycystic ovary syndrome: could it be the visceral adiposity index?en_US
dc.departmentAFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.contributor.institutionauthorApaydın, Mahmut
dc.contributor.institutionauthorDizen Kazan, Elif
dc.contributor.institutionauthorBeysel, Selvihan
dc.contributor.institutionauthorSarı, Alper
dc.contributor.institutionauthorÖzgül, Esra
dc.contributor.institutionauthorYılmazer, Mehmet
dc.relation.journalEuropean Review for Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

Files in this item


This item appears in the following Collection(s)

Show simple item record