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dc.contributor.authorDural, İbrahim Etem
dc.contributor.authorOnrat, Ersel
dc.contributor.authorÇelik, Sefa
dc.contributor.authorVurmaz, Ayhan
dc.contributor.authorYalım, Zafer
dc.contributor.authorGökaslan, Serkan
dc.contributor.authorGökaslan, Çiğdem
dc.contributor.authorKorucu, Cem
dc.contributor.authorAksu, Uğur
dc.date.accessioned2022-07-28T11:51:05Z
dc.date.available2022-07-28T11:51:05Z
dc.date.issued2022en_US
dc.identifier.citationDural, İ. E., Onrat, E., Çelik, S., Vurmaz, A., Yalım, Z., Gökaslan, S., ... & Aksu, U. (2022). The Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure.en_US
dc.identifier.issn1308-4488
dc.identifier.urihttps://doi.org/10.5543/tkda.2022.21249
dc.identifier.urihttps://hdl.handle.net/20.500.12933/1391
dc.description.abstractObjective: Dietary recommendations, in addition to medications, have recently become important in the treatment of heart failure. Our study aimed to show the positive effects of both milk chocolate and dark chocolate on heart failure through endothelial functions. Methods: Twenty patients with heart failure and reduced ejection fraction were included in the study. In this randomized, crossover study, some of the patients consumed milk chocolate and some consumed dark chocolate. We recorded the patients' 6-minute walking tests, flow- mediated dilatation values, plasma catechin, epicatechin, and N-terminal pro-brain natri- uretic peptide values before and after chocolate consumption. After 2 weeks, their chocolate consumption was changed. The same parameters were measured again. Results: A significant decrease was observed in N-terminal pro-brain natriuretic peptide values after consumption of both milk chocolate (356 ± 54.2 and 310 ± 72.1 pg/mL; P = .007) and dark chocolate (341 ± 57 and 301 ± 60.1 pg/mL;P=.028). Flow-mediated dilation values increased after dark chocolate consumption (8.9 ± 3% and 14 ± 4.5%; P = .019). Conclusion: Chocolate consumption acutely decreases N-terminal pro-brain natriuretic pep- tide values in heart failure. Dark chocolate consumption also seems to improve endothelial functions by increasing flow-mediated dilation values.en_US
dc.language.isoengen_US
dc.publisherAVES Yayıncılıken_US
dc.relation.isversionof10.5543/tkda.2022.21249en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeart failureen_US
dc.subjectChocolateen_US
dc.subjectFlow-mediated dilationen_US
dc.subjectKalp yetersizliğien_US
dc.subjectÇikolataen_US
dc.subjectAkım aracılı dilatasyonen_US
dc.titleThe Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failureen_US
dc.title.alternativeKalp Yetmezliği Hastalarında Çikolata Tüketimi ile Endotel Disfonksiyonu Arasındaki İlişkinin Belirlenmesien_US
dc.typearticleen_US
dc.authorid0000-0003-4005-4858en_US
dc.authorid0000-0002-2215-6570en_US
dc.authorid0000-0001-7758-9034en_US
dc.authorid0000-0002-1840-2900en_US
dc.authorid0000-0001-7736-0205en_US
dc.authorid0000-0001-7268-178Xen_US
dc.authorid0000-0001-5345-1735en_US
dc.authorid0000-0003-2769-3495en_US
dc.authorid0000-0003-0918-5032en_US
dc.departmentAFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.contributor.institutionauthorDural, İbrahim Etem
dc.contributor.institutionauthorOnrat, Ersel
dc.contributor.institutionauthorÇelik, Sefa
dc.contributor.institutionauthorVurmaz, Ayhan
dc.contributor.institutionauthorYalım, Zafer
dc.contributor.institutionauthorGökaslan, Serkan
dc.contributor.institutionauthorGökaslan, Çiğdem
dc.contributor.institutionauthorKorucu, Cem
dc.contributor.institutionauthorAksu, Uğur
dc.identifier.volume50en_US
dc.identifier.issue5en_US
dc.identifier.startpage334en_US
dc.identifier.endpage339en_US
dc.relation.journalTürk Kardiyoloji Derneği Arşivien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US


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