dc.contributor.author | Dural, İbrahim Etem | |
dc.contributor.author | Sarı, Alper | |
dc.contributor.author | Ersoy, İbrahim | |
dc.date.accessioned | 2022-07-28T09:48:19Z | |
dc.date.available | 2022-07-28T09:48:19Z | |
dc.date.issued | 21.07.2022 | en_US |
dc.identifier.citation | Dural, İ. E., Sarı, A., & Ersoy, İ. (2022). Effects of 3 months of treatment with empagliflozin on left ventricle global longitudinal strain and myocardial mechano‐energetic effiency. Echocardiography. | en_US |
dc.identifier.issn | 1540-8175 | |
dc.identifier.uri | https://doi.org/10.1111/echo.15424 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12933/1389 | |
dc.description.abstract | Purpose: Sodium glucose transporter-2 (SGLT-2) inhibitors are employed in the treatment of cardiovascular diseases such as heart failure and coronary artery disease. In the present study, we aimed to investigate how Empagliflozin in SGLT 2 inhibitors affects cardiac contraction and pump efficiency in patients who have Diabetes Mellitus (DM) without cardiovascular disease.
Methods: The conventional echocardiographic records and biochemical values of 62 patients who had DM without a history of cardiovascular disease were evaluated before using Empagliflozin. The myocardial mechano-energetic (MME) activity and index, and global longitudinal strain (GLS) were also calculated. After 3 months of Empagliflozin use, the tests were repeated and compared with previous data. A p < .05 was considered statistically significant.
Results: Left ventricular GLS and MME efficiency were found to be significantly higher after treatment (-17.71 ± 2.12, -19.15 ± .71; p < .001 and 62.14 ± 18.21, 72.24 ± 26.57; p: .019).
Conclusion: An increase was detected in left ventricular longitudinal strain and MME efficiency after using Empagliflozin for 3 months in patients with DM. This result suggests that Empagliflozin improves left ventricular pump efficiency and contraction. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley-Blackwell | en_US |
dc.relation.isversionof | 10.1111/echo.15424 | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Empagliflozin | en_US |
dc.subject | Globallongitudinalstrain | en_US |
dc.subject | Myocardialmechano-energeticeffiency | en_US |
dc.title | Effects of 3 months of treatment with empagliflozin on left ventricle global longitudinal strain and myocardial mechano-energetic effiency | en_US |
dc.type | article | en_US |
dc.authorid | 0000-0003-4005-4858 | en_US |
dc.authorid | 0000-0002-4327-8032 | en_US |
dc.authorid | 0000-0002-9553-8801 | en_US |
dc.department | AFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | en_US |
dc.contributor.institutionauthor | Dural, İbrahim Etem | |
dc.contributor.institutionauthor | Sarı, Alper | |
dc.contributor.institutionauthor | Ersoy, İbrahim | |
dc.identifier.startpage | 1 | en_US |
dc.identifier.endpage | 6 | en_US |
dc.relation.journal | Echocardiography | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |