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dc.contributor.authorDural, İbrahim Etem
dc.contributor.authorSarı, Alper
dc.contributor.authorErsoy, İbrahim
dc.date.accessioned2022-07-28T09:48:19Z
dc.date.available2022-07-28T09:48:19Z
dc.date.issued21.07.2022en_US
dc.identifier.citationDural, İ. E., Sarı, A., & Ersoy, İ. (2022). Effects of 3 months of treatment with empagliflozin on left ventricle global longitudinal strain and myocardial mechano‐energetic effiency. Echocardiography.en_US
dc.identifier.issn1540-8175
dc.identifier.urihttps://doi.org/10.1111/echo.15424
dc.identifier.urihttps://hdl.handle.net/20.500.12933/1389
dc.description.abstractPurpose: Sodium glucose transporter-2 (SGLT-2) inhibitors are employed in the treatment of cardiovascular diseases such as heart failure and coronary artery disease. In the present study, we aimed to investigate how Empagliflozin in SGLT 2 inhibitors affects cardiac contraction and pump efficiency in patients who have Diabetes Mellitus (DM) without cardiovascular disease. Methods: The conventional echocardiographic records and biochemical values ​​of 62 patients who had DM without a history of cardiovascular disease were evaluated before using Empagliflozin. The myocardial mechano-energetic (MME) activity and index, and global longitudinal strain (GLS) were also calculated. After 3 months of Empagliflozin use, the tests were repeated and compared with previous data. A p < .05 was considered statistically significant. Results: Left ventricular GLS and MME efficiency were found to be significantly higher after treatment (-17.71 ± 2.12, -19.15 ± .71; p < .001 and 62.14 ± 18.21, 72.24 ± 26.57; p: .019). Conclusion: An increase was detected in left ventricular longitudinal strain and MME efficiency after using Empagliflozin for 3 months in patients with DM. This result suggests that Empagliflozin improves left ventricular pump efficiency and contraction.en_US
dc.language.isoengen_US
dc.publisherWiley-Blackwellen_US
dc.relation.isversionof10.1111/echo.15424en_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectEmpagliflozinen_US
dc.subjectGloballongitudinalstrainen_US
dc.subjectMyocardialmechano-energeticeffiencyen_US
dc.titleEffects of 3 months of treatment with empagliflozin on left ventricle global longitudinal strain and myocardial mechano-energetic effiencyen_US
dc.typearticleen_US
dc.authorid0000-0003-4005-4858en_US
dc.authorid0000-0002-4327-8032en_US
dc.authorid0000-0002-9553-8801en_US
dc.departmentAFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.contributor.institutionauthorDural, İbrahim Etem
dc.contributor.institutionauthorSarı, Alper
dc.contributor.institutionauthorErsoy, İbrahim
dc.identifier.startpage1en_US
dc.identifier.endpage6en_US
dc.relation.journalEchocardiographyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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