dc.contributor.author | Orhan, Semiha | |
dc.contributor.author | Taşdemir Mecit, Bilge Banu | |
dc.contributor.author | Dizen Kazan, Elif | |
dc.contributor.author | Kazan, Sinan | |
dc.contributor.author | Şarlak Konya, Petek | |
dc.contributor.author | Gülsoy, Kemal Yetiş | |
dc.date.accessioned | 2022-06-14T08:10:33Z | |
dc.date.available | 2022-06-14T08:10:33Z | |
dc.date.issued | 16.09.2021 | en_US |
dc.identifier.citation | Orhan, S., Mecit, B. B. T., Kazan, E. D., Kazan, S., Konya, P. Ş., & Gulsoy, K. Y. (2021). The effect of acute phase reactants on the survival of COVID-19 patients in intensive care. Progress in Nutrition. | en_US |
dc.identifier.issn | 1129-8723 | |
dc.identifier.uri | https://doi.org/10.23751/PN.V23IS2.12046 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12933/1159 | |
dc.description.abstract | Study Objectives: The aim of this study was to investigate the relationship between the biomarkers of serum CRP, PCT, D-dimer, ferritin, and lymphocytes, and the survival of COVID-19 patients admitted to the Intensive Care Unit (ICU). Methods: The effect of acute phase reactants on survival were retrospectively examined in 399 patients diagnosed with COVID-19 and followed up in the ICU of Afyonkarahisar Health Sciences University Medical Faculty Hospital between 20 March 2020 and 31 December 2020. Results: The 399 patients included in the study comprised 273 (68.4%) males and 126 (31.6%) females with a median age of 68 years (IQR: 15 years). Mortality developed in 225 (56.4%) patients in ICU and 174 (43.6%) were discharged. In the ROC analysis applied to CRP, PCT, D-dimer, ferritin levels, and lymphocyte count, the AUC values were determined in the range of 0.389-0.635. D-dimer was the parameter with the highest AUC value. In the survival analysis according to the cutoff values determined for CRP, PCT, D-dimer, and lymphocyte count, these four parameters were determined to have an effect on survival (p = 0.038, p = 0.001, p = 0.012, and p = 0.018, respectively). Ferritin levels were found to be similar between the groups of survivors and non-survivors (p = 0.492). Conclusion: High serum CRP, PCT, D-dimer levels, and low lymphocyte count were determined to be associated with poor outcomes in the 399 patients admitted to the ICU with a diagnosis of severe COVID-19 pneumonia. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Mattioli 1885 | en_US |
dc.relation.isversionof | 10.23751/PN.V23IS2.12046 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Inflammatory | en_US |
dc.subject | Acute phase reactant | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Intensive care | en_US |
dc.title | The Effect of Acute Phase Reactants on the Survival of COVID-19 Patients in Intensive Care | en_US |
dc.type | article | en_US |
dc.authorid | 0000-0003-2617-6197 | en_US |
dc.authorid | 0000-0002-7994-7816 | en_US |
dc.authorid | 0000-0003-3550-0964 | en_US |
dc.authorid | 0000-0001-7290-4680 | en_US |
dc.authorid | 0000-0001-5055-1220 | en_US |
dc.department | AFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.contributor.institutionauthor | Orhan, Semiha | |
dc.contributor.institutionauthor | Taşdemir Mecit, Bilge Banu | |
dc.contributor.institutionauthor | Dizen Kazan, Elif | |
dc.contributor.institutionauthor | Kazan, Sinan | |
dc.contributor.institutionauthor | Şarlak Konya, Petek | |
dc.identifier.volume | 23 | en_US |
dc.identifier.startpage | 1 | en_US |
dc.identifier.endpage | 7 | en_US |
dc.relation.journal | Progress in Nutrition | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |