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dc.contributor.authorDemir, Hacer
dc.contributor.authorÇağlayan, D
dc.contributor.authorKaman, O
dc.contributor.authorİnanç, M
dc.contributor.authorUrvay, Semiha
dc.contributor.authorBeypınar, İsmail
dc.contributor.authorDemirci, A
dc.contributor.authorDavarcı, Sena Ece
dc.contributor.authorAraz, M
dc.contributor.authorBaykara, Meltem
dc.contributor.authorArtaç, M
dc.contributor.authorYıldız, F
dc.date.accessioned2022-05-16T07:47:16Z
dc.date.available2022-05-16T07:47:16Z
dc.date.issued2022en_US
dc.identifier.citationDemir, H., Caglayan, D., Kaman, O., İnanc, M., Urvay, S., Beypinar, I., ... & Yildiz, F. (2022). Evaluating the effect of tumor size and sidedness on prognosis in stage 2 colon cancer: a retrospective population study. Eur Rev Med Pharmacol Sci, 26(4), 1328-1340.en_US
dc.identifier.issn2284-0729
dc.identifier.urihttps://doi.org/10.26355/eurrev_202202_28126
dc.identifier.urihttps://hdl.handle.net/20.500.12933/1010
dc.description.abstractOBJECTIVE: In this study, we aimed to evaluate the effect of tumor size and tumor sidedness on prognosis in patients with stage 2 colon cancer. PATIENTS AND METHODS: Data of 501 patients diagnosed with stage 2 colon cancer were evaluated retrospectively. It was evaluated whether the patients’ age, gender, tumor differentiation, tumor node metastasis (TNM) stage, overall survival rate, and disease-free survival rate had any correlation with horizontal tumor diameter and tumor sidedness. In the ROC analysis performed to determine the cut-off value for the tumor diameter, which we think will predict survival, no significant results were obtained with maximum sensitivity and specificity. Therefore, the median value of the tumor diameter, which is 5 cm, was accepted as the cut-off value. Kaplan-Meier method and Cox regression analysis were used for survival analysis and determination of prognostic factors. RESULTS: When the patients were evaluated in terms of tumor localization, 189 (37.7%) patients had right colon tumors and 312 (62.3%) patients had left colon tumors. There was no statistically significant difference in terms of disease-free survival and overall survival according to tumor localization. When the patients were analyzed by dividing them into two groups according to the horizontal tumor size (<5 cm and ≥5 cm), no statistically significant difference was found between the groups in terms of disease-free survival (DFS) and overall survival (OS) p=0.085, p=0.699, respectively. CONCLUSIONS: Our results suggest that the management of patients with stage 2 colon cancer requires a better understanding of tumor biology rather than features such as tumor size and localization.en_US
dc.language.isoengen_US
dc.publisherVerducien_US
dc.relation.isversionof10.26355/eurrev_202202_28126en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColon canceren_US
dc.subjectTumor sizeen_US
dc.subjectTumor sidednessen_US
dc.subjectPrognosisen_US
dc.titleEvaluating the effect of tumor size and sidedness on prognosis in stage 2 colon cancer: a retrospective population studyen_US
dc.typearticleen_US
dc.authorid0000-0003-1235-9363en_US
dc.authorid0000-0003-1142-9411en_US
dc.authorid0000-0003-3291-8134en_US
dc.departmentAFSÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.contributor.institutionauthorDemir, Hacer
dc.contributor.institutionauthorDavarcı, Sena Ece
dc.contributor.institutionauthorBaykara, Meltem
dc.identifier.volume26en_US
dc.identifier.issue4en_US
dc.identifier.startpage1328en_US
dc.identifier.endpage1340en_US
dc.relation.journalEuropean Review for Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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