Scopus İndeksli Yayınlar KoleksiyonuScopus Indexed Publications Collectionhttps://hdl.handle.net/20.500.12933/32024-03-29T02:23:58Z2024-03-29T02:23:58ZA Modeling Study on Science Teachers’ Sustainable Development Knowledge, Attitudes and PracticesPamuk, SavaşElmas, RıdvanSaban, Yakuphttps://hdl.handle.net/20.500.12933/14322022-10-20T06:28:25Z0022-01-01T00:00:00ZA Modeling Study on Science Teachers’ Sustainable Development Knowledge, Attitudes and Practices
Pamuk, Savaş; Elmas, Rıdvan; Saban, Yakup
This study investigates possible predictors of science teachers’ education for sustainable
development (ESD) practices by controlling their significant life experiences (SLE), knowledge
and attitudes about sustainable development (SD), and schools’ environment. Fifty schools and
376 teachers participated in the study. A survey was conducted investigating teachers’ demographic
information and their knowledge and attitude about SD and ESD practices. Their schools were
examined as ESD facilitators. Teachers’ SLE was a significant predictor of their knowledge and
attitude about SD and their ESD practices. Besides, teachers’ knowledge about SD predicted their
attitude towards SD. Their attitude towards SD and SLE predicted their ESD practices. Also, schools’
physical environment was not a significant predictor of any teacher-related variables.
0022-01-01T00:00:00ZThe effects of the ethanol extract of Cordia myxa leaves on the cognitive function in miceKendir, GülsenBae, Ho JungJeong, YongwooBae, Hyo JeoungPark, KeontaeYang, XingquanCho, Young‑jinKim, Ji‑YoungJung, Seo YunKöroğlu, AyşegülJang, Dae SikRyu, Jong Hoonhttps://hdl.handle.net/20.500.12933/13962022-08-29T06:07:48Z0010-01-01T00:00:00ZThe effects of the ethanol extract of Cordia myxa leaves on the cognitive function in mice
Kendir, Gülsen; Bae, Ho Jung; Jeong, Yongwoo; Bae, Hyo Jeoung; Park, Keontae; Yang, Xingquan; Cho, Young‑jin; Kim, Ji‑Young; Jung, Seo Yun; Köroğlu, Ayşegül; Jang, Dae Sik; Ryu, Jong Hoon
Background
Cordia myxa L. (Boraginaceae) is widely distributed in tropical regions and it’s fruits, leaves and stem bark have been utilized in folk medicine for treating trypanosomiasis caused by Trypanosoma cruzi. A population-based study showed that T. cruzi infection is associated with cognitive impairments. Therefore, if C. myxa has ameliorating activities on cognitive function, it would be useful for both T. cruzi infection and cognitive impairments.
Methods
In this study, we evaluated the effects of an ethanol extract of leaves of C. myxa (ELCM) on memory impairments and sensorimotor gating deficits in mice. The phosphorylation level of protein was observed by the Western blot analysis.
Results
The administration of ELCM significantly attenuated scopolamine-induced cognitive dysfunction in mice, as measured by passive avoidance test and novel object recognition test. Additionally, in the acoustic startle response test, we observed that the administration of ELCM ameliorated MK-801-induced prepulse inhibition deficits. We found that these behavioral outcomes were related with increased levels of phosphorylation phosphatidylinositol 3-kinase (PI3K), protein kinase B (Akt) and glycogen synthase kinase 3 beta (GSK-3β) in the cortex and extracellular signal-regulated kinase (ERK) and cAMP response element-binding protein (CREB) in the hippocampus by western blot analysis.
Conclusions
These results suggest that ELCM would be a potential candidate for treating cognitive dysfunction and sensorimotor gating deficits observed in individuals with neurodegenerative diseases.
0010-01-01T00:00:00ZThe Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart FailureDural, İbrahim EtemOnrat, ErselÇelik, SefaVurmaz, AyhanYalım, ZaferGökaslan, SerkanGökaslan, ÇiğdemKorucu, CemAksu, Uğurhttps://hdl.handle.net/20.500.12933/13912022-07-28T11:51:06Z2022-01-01T00:00:00ZThe Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure
Dural, İbrahim Etem; Onrat, Ersel; Çelik, Sefa; Vurmaz, Ayhan; Yalım, Zafer; Gökaslan, Serkan; Gökaslan, Çiğdem; Korucu, Cem; Aksu, Uğur
Objective: Dietary recommendations, in addition to medications, have recently become important in the treatment of heart failure. Our study aimed to show the positive effects of both milk chocolate and dark chocolate on heart failure through endothelial functions.
Methods: Twenty patients with heart failure and reduced ejection fraction were included in the study. In this randomized, crossover study, some of the patients consumed milk chocolate and some consumed dark chocolate. We recorded the patients' 6-minute walking tests, flow- mediated dilatation values, plasma catechin, epicatechin, and N-terminal pro-brain natri- uretic peptide values before and after chocolate consumption. After 2 weeks, their chocolate consumption was changed. The same parameters were measured again.
Results: A significant decrease was observed in N-terminal pro-brain natriuretic peptide values after consumption of both milk chocolate (356 ± 54.2 and 310 ± 72.1 pg/mL; P = .007) and dark chocolate (341 ± 57 and 301 ± 60.1 pg/mL;P=.028). Flow-mediated dilation values increased after dark chocolate consumption (8.9 ± 3% and 14 ± 4.5%; P = .019).
Conclusion: Chocolate consumption acutely decreases N-terminal pro-brain natriuretic pep- tide values in heart failure. Dark chocolate consumption also seems to improve endothelial functions by increasing flow-mediated dilation values.
2022-01-01T00:00:00ZMortality Trends from Ischemic Heart Disease in Turkey: 2009-2019Yalım, ZaferDoğan, NurhanAlan Yalım, Sümeyrahttps://hdl.handle.net/20.500.12933/13902022-07-28T11:35:28Z2022-01-01T00:00:00ZMortality Trends from Ischemic Heart Disease in Turkey: 2009-2019
Yalım, Zafer; Doğan, Nurhan; Alan Yalım, Sümeyra
Objective: Cardiovascular diseases still play an important role in public health and epidemiol- ogy as the leading cause of death worldwide. Ischemic heart disease is the most common reason in this group. This study aims to analyze the latest trends in ischemic heart disease mor- tality rates in Turkey by age, gender, and region using the Turkish Statistical Institute mortality data and evaluate the results.
Methods: We have obtained ischemic heart disease mortality data (2009-2019, in 12 regions) for Turkey from the mortality database of the Turkish Statistical Institute. Joinpoint analysis was used to estimate the annual percentage change and average annual percentage change to identify significant changes in trends.
Results: The mean mortality rate for ischemic heart disease in Turkey was in an increasing trend from 2009 to 2019 (annual percentage change=1.7 (-0.8; 4.3), P=.166). This increase was more pronounced in women (annual percentage change=2.2 (-0.7; 5.2), P=.121) compared to men (annual percentage change=1.4 (-1.1; 3.9), P=.235). When the period between 2015 and 2019 was evaluated, it was determined that ischemic heart disease mortality was in a decreasing trend in the groups over 65 years of age. The death rate due to ischemic heart disease is almost 2 times higher in men than in women in Turkey, and this rate ratio is highest in the Istanbul region.
Conclusion: Although ischemic heart disease mortality trends have decreased globally, our country's average is still on an increasing trend. However, significant decreases have been observed in ischemic heart disease mortality rates, especially in the group over 65 years of age, in the last 5 years.
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