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Toplam kayıt 13, listelenen: 1-10
In Vitro Investigation of the Effects of Cape Contribution to Chemotherapeutic Drug Treatment on the Neuroblastoma Cell Line (SH SY- 5Y) on the Inflammatory Process
(Gaziantep İslam Bilim ve Teknoloji Üniversitesi, 2022)
Neuroblastoma is a sympathetic nervous system tumor with a 5-year survival rate of less than 50% in high-risk patients that are unresponsive to conventional multimodal treatments. Although chemotherapy, radiotherapy, and ...
The effects of taxifolin on alveolar bone in experimental periodontitis in rats
(Pergamon-Elsevier Science Ltd, 2020)
Objective: This study aimed to evaluate the effect of taxifolin, a powerful antioxidant, on the progression of periodontitis by immunohistochemical and cone-beam computed tomography (CBCT) examination. Design: This study ...
The effects of intravitreal H2S application on apoptosis in the retina and cornea in experimental glaucoma model
(Wiley, 2019)
One of the most important causes of visual loss (blindness) is glaucoma, which occurs due to the degeneration of the ganglion cells in retina. It has been shown that hydrogen sulphide (H2S) acts an antioxidant, neuroprotective ...
Proteomic analysis of the anticancer effect of various extracts of endemicThermopsis turcica in human cervical cancer cells
(Turkiye Klinikleri, 2020)
Background/aim: Thermopsis turcica is a perennial species endemic to Turkey and different extracts of T. turcica have an antiproliferative effect on cancer cells, but there has not been any report on HeLa (human cervical ...
Plasma galectin-3 as a biomarker for clinical staging of heart failure: A cross-sectional evaluation of 100 cases
(Societa Editrice Universo, 2019)
Objectives. To evaluate the plasma galectin-3 concentration associated with the severity of HF and its use as a biomarker for clinical staging of heart failure (HF). Method. This was a cross-sectional study, in which 100 ...
Effects of resveratrol and 1,3-bis(2-chloroethyl)-1-nitrosurea combination on YKG1 glioblastoma cells
(Abdullah KAYA, 2021)
Glioblastoma is a primary malignant brain tumor that can be treated with 1,3-bis(2-chloroethyl)-1-nitrosurea(BiCNU/carmustine). Resveratrol is a natural phenol that can interfere with apoptosis. This study aims to investigate ...
Effects of Panax ginseng on cisplatin-induced testicular damage of rats
(Abdullah KAYA, 2021)
Abstract: Infertility has become an increasingly important health problem due to genetic, familial, hormonal, and congenital
abnormalities, environmental and chemical reasons. This study aimed to investigate the effects ...
Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction
(Elsevier, 01.10.2022)
Chronic myelogenous leukemia (CML) is characterized by Philadelphia translocation arising from Bcr-Abl fusion gene, which encodes abnormal oncoprotein showing tyrosine kinase (TK) function. Certain mutations in kinase ...
Investigation of the effect of rhamnetin on mice injected with solid and ehrlich ascites tumor
(Springer, 2023)
Rhamnetin is a flavonoid which contained in especially clove, such as apple, tea, and onion plant. Rhamnetin has been used in cancer research due to its antitumor and antioxidant properties. In this study, effects of ...
The role of SIRT2 inhibition on the aging process of brain in male rats
(Elsevier, 2023)
Background: Though the exact mechanisms regarding brain aging and its relation to neurodegenerative disorders are not precise, oxidative stress, the key regulators of apoptosis and autophagy, such as bcl-2 and beclin 1, ...