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Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region-associated protein synthesis and TLR4/NF-κB signaling pathway
Yılmaz, Seher; Doğanyiğit, Züleyha; Oflamaz, Aslı Okan; Ateş, Şükrü; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna (Wiley-Blackwell, 2022)In this study, the protective effect of melatonin was investigated in lipopolysaccharide induced sepsis model. Twenty-eight rats were randomly divided: Control, Melatonin, LPS and LPS + Melatonin. After LPS application, ... -
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-κB/TNF-α signaling pathways: Experimental study
Okan, Aslı; Doğanyiğit, Züleyha; Yılmaz, Seher; Uçar, Sümeyye; Arıkan Söylemez, Evrim Suna; Attar, Rukset (Wiley-Blackwell, 2023)The development and progression of sepsis are multifactorial and influence the immunological, endocrine, and cardiovascular systems of the body. Our knowledge of the key mechanisms involved in the pathogenesis of sepsis ...